Functional outcome after Ivor Lewis esophagectomy for cancer
Functional outcome after Ivor Lewis esophagectomy for cancer
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DOI：
10.1002/jso.24084
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发表时间：
2016-01-01
影响因子：
2.5
通讯作者：
Pattyn, Piet
中科院分区：
文献类型：
--
作者：
Deldycke, Annelies;Van Daele, Elke;Pattyn, Piet
BackgroundLittle是已知的Ivor刘易斯食管切除术（ILE）与intrathoracic anastomosis.MethodsPatients谁接受ILE从一个前瞻性的数据库。检索临床病理数据，并与基于患者通过标准问卷自我评估的功能结局数据进行比较。选定的功能投诉的预测因素进行了确定与Logistic回归analysis. ResultsThirty百和22例（80.4%男性，平均年龄62岁）进行了研究。手术适应症为腺癌（62.4%）、鳞状细胞癌（28%）和HG Barrett异型增生（7%）。42.5%的患者接受了术前放化疗（CRT）。吻合口漏发生率为5.6%，与较高的年龄和糖尿病相关。确定的功能症状为反流（39%）、胃排空延迟（37%）、倾倒（21.4%）和吻合口狭窄（16%）。在多变量模型中，吻合口狭窄与吻合器直径较小和食管炎相关。术后反流与较高的BMI相关，而倾倒是由女性性别和年龄预测的。生活质量问卷调查显示，在82%的patients.ConclusionsFunctional投诉后ILE包括反流，胃排空延迟，倾倒，吞咽困难，并受年龄，性别，BMI，糖尿病，吻合器直径的一般健康状况良好。《肿瘤外科杂志》2016;113：24-28. (c)2015年威利期刊公司
BackgroundLittle is known on functional outcome after Ivor Lewis esophagectomy (ILE) with intrathoracic anastomosis.MethodsPatients who underwent ILE were identified from a prospective database. Clinicopathological data were retrieved and compared with functional outcome data based on patient self-assessment by a standard questionnaire. Predictive factors for selected functional complaints were identified with logistic regression analyses.ResultsThree hundred and twenty-two patients (80.4% male, mean age 62 years) were studied. Indications for surgery were adenocarcinoma (62.4%), squamous cell carcinoma (28%), and HG Barrett dysplasia (7%). Preoperative chemoradiation (CRT) was administered to 42.5% of patients. Anastomotic leakage occurred in 5.6% and was associated with higher age and diabetes mellitus. Functional symptoms identified were reflux (39%), delayed gastric emptying (37%), dumping (21.4%), and anastomotic stenosis (16%). In the multivariate models, anastomotic stenosis was associated with smaller stapler diameter and presence of esophagitis. Postoperative reflux was associated with higher BMI, whereas dumping was predicted by female gender and age. The quality of life questionnaires revealed a good general health status in 82% of the patients.ConclusionsFunctional complaints after ILE consist of reflux, delayed gastric emptying, dumping, and dysphagia, and are affected by age, gender, BMI, diabetes mellitus, and stapler diameter. J. Surg. Oncol. 2016;113:24-28. (c) 2015 Wiley Periodicals, Inc.