Extension of single scatter simulation to scatter correction of time-of-flight PET
Extension of single scatter simulation to scatter correction of time-of-flight PET
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DOI：
10.1109/tns.2007.901227
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发表时间：
2007-10-01
影响因子：
1.8
通讯作者：
Watson, Charles C.
中科院分区：
文献类型：
--
作者：
Watson, Charles C.
我们扩展了三维正电子发射断层扫描散射校正的单次散射模拟（SSS）算法，以包括根据其差分飞行时间（TOF）来区分散射湮灭辐射的情况。在体模和人体数据中观察到计算的和测量的TOF相关散射之间的良好一致性。TOF相关和非TOF相关散射之间存在显著差异，因为TOF评分消除了射线总和计算中的简并性，TOF SSS需要比非TOF SSS长约7倍的时间来计算散射正弦图本身。然而，当考虑到由于图像计算和迭代引起的开销时，临床性能只是较慢的一个因素。
We extend the single scatter simulation (SSS) algorithm for scatter correction of three dimensional positron emission tomography to include the case in which the scattered annihilation radiation is discriminated according to its differential time-of-flight (TOF). Good agreement between computed and measured TOF dependent scatter is observed in phantom and human data. Significant differences between TOF dependent and non-TOF dependent scatter are found. Because TOF scoring removes the degeneracy in ray sum calculations, TOF SSS takes about seven times longer than non-TOF SSS to compute the scatter sinogram itself. However, when the overhead due to image computation and iteration is factored in, the clinical performance is only a factor of slower.