Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy
Rapid Generation of Complex Molecular Architectures by a Catalytic Enantioselective Dearomatization Strategy
复制标题
通过催化对映选择性脱芳构化策略快速生成复杂分子结构
作者：
Gaunt M
催化对映选择性脱芳构化策略可用于将容易组装的酚转化为复杂的多环结构。通过将带有侧链亲核试剂的酚类化合物的氧化脱芳构化与对映选择性仲胺催化相结合，获得了类似天然产物的高对映体过量。
A catalytic enantioselective dearomatization strategy can be used to convert readily assembled phenols into complex polycyclic architectures. By combining oxidative dearomatization of phenols bearing a pendent nucleophile with enantioselective secondary amine catalysis, high enantiomeric excesses were obtained for the natural product-like products.