Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale
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DOI：
10.1590/1806-9282.63.07.590
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发表时间：
2017-07-01
期刊：
影响因子：
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通讯作者：
Bicalho, Maria Aparecida Camargos
中科院分区：
文献类型：
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作者：
Cintra, Fabiana Carla Matos da Cunha;Cintra, Marco Túlio Gualberto;Bicalho, Maria Aparecida Camargos
目的：将阿尔茨海默病日常生活活动（ADCS-ADL）量表作为认知筛查工具，在巴西葡萄牙语中进行翻译、跨文化适应和应用。方法：采用加前测和双语的回译方法。样本由95名老年人和他们的照顾者组成。32名参与者被诊断为轻度认知障碍（MCI）患者，33名被诊断为阿尔茨海默病（AD）患者，30名被认为是认知正常的个体。结果：两组患者量表变化不大。Cronbach α系数为0.89。对照组得分为72.9分，MCI得分为65.1分，AD得分为55.9分，p值均< 0.001。ROC曲线值为0.89。我们考虑切点为72，我们观察到敏感性为86.2%，特异性为70%，阳性预测值为86.2%，阴性预测值为70%，阳性似然比为2.9，阴性似然比为0.2。结论：ADCS-ADL量表对轻度认知障碍、AD和正常认知具有满意的心理测量特性。
Objective: Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument.Method: We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer's disease (AD) patients and 30 were considered as cognitively normal individuals.Results: There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2.Conclusion: ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.