Introduction to the Compendium on calcific aortic valve disease.

Introduction to the Compendium on calcific aortic valve disease.
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DOI:
10.1161/circresaha.113.301833
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发表时间:
2013-07-05
影响因子:
20.1
通讯作者:
Demer LL
Demer LL
中科院分区:
医学1区
文献类型:
--
作者:
Heistad DD;Shanahan C;Demer LL

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On the Compendium cover: Aortic valve disease in an Ldlr-/-Apob100/100 mouse. α-smooth muscle actin (green), which indicates fibroblast transactivation to myofibroblasts or smooth muscle cell migration, is present throughout the valve. Activated caspase-3 (red), a marker for programmed cell death, is concentrated at sites of valve cusp attachment and in atheroma in aortic annulus. Cell nuclei are stained blue. From: Yi Chu, Robert Weiss, and Donald Heistad.