DNA replication and recombination

DNA replication and recombination
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DOI:
10.1038/nature01407
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发表时间:
2003-01-23
期刊:
影响因子:
64.8
通讯作者:
Alberts, B
Alberts, B
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Alberts, B

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对 DNA 结构的了解使科学家能够承担破译生命核心的两个动态过程的详细分子机制的艰巨任务:通过 DNA 复制复制遗传信息,以及通过 DNA 重组进行重排和修复。尽管过去五年在实现这一目标方面取得了巨大进展,但下一代分子生物学家仍然面临许多挑战。
Knowledge of the structure of DNA enabled scientists to undertake the difficult task of deciphering the detailed molecular mechanisms of two dynamic processes that are central to life: the copying of the genetic information by DNA replication, and its reassortment and repair by DNA recombination. Despite dramatic advances towards this goal over the past five decades, many challenges remain for the next generation of molecular biologists.