Combined PET-CT in the head and neck Part 1. Physiologic, altered physiologic, and artifactual FDG uptake
Combined PET-CT in the head and neck Part 1. Physiologic, altered physiologic, and artifactual FDG uptake
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DOI：
10.1148/rg.254035156
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发表时间：
2005-07-01
期刊：
影响因子：
5.5
通讯作者：
Meltzer, CC
中科院分区：
文献类型：
--
作者：
Blodgett, TM;Fukui, MB;Meltzer, CC
使用 2-[氟-18] 氟-2-脱氧-D-葡萄糖 (FDG) 的正电子发射断层扫描 (PET) 对于头颈部恶性肿瘤的诊断、分期和再分期非常有效。然而，缺乏解剖标志、可变的生理摄取以及在几种改变的生理状态下 FDG 分布不对称可能会混淆图像解释。此外，许多良性原因和一些伪影可以模拟头部和颈部的生理或病理性 FDG 摄取。组合 PET - 计算机断层扫描 (CT) 是一种独特的成像方式，可以在一台扫描仪上进行解剖和功能成像，并具有近乎完美的配准。 PET-CT 组合可提供单独使用 PET 或 CT 无法获得的信息。特别是，PET-CT 有助于解释头部和颈部的 FDG 摄取，该区域的解剖结构密集且复杂。根据 11,000 名患者的 PET-CT 综合结果，编制了该解剖区域 FDG 摄取图谱。一般来说，FDG 摄取模式是可变的，通常反映了摄取阶段期间或之前的患者活动。随着人们对 PET-CT 的兴趣日益浓厚，解读放射科医生和核医学医师必须熟悉头颈部 FDG 的摄取模式，以避免误解或误诊。 (c) 北美放射学会，2005 年。
Positron emission tomography (PET) with 2-[fluorine-18] fluoro-2-deoxy-D-glucose (FDG) has been effective for the diagnosis, staging, and restaging of malignancies of the head and neck region. However, lack of anatomic landmarks, variable physiologic uptake, and asymmetric FDG distribution in several altered physiologic states can confound image interpretation. In addition, many benign causes and several artifacts can simulate physiologic or pathologic FDG uptake in the head and neck. Combined PET - computed tomography (CT) is a unique imaging modality that permits anatomic and functional imaging on a single scanner with nearly perfect coregistration. Combined PET-CT provides information that cannot be obtained with PET or CT alone. In particular, PET-CT facilitates the interpretation of FDG uptake in the head and neck, an area that is characterized by dense and complex anatomic structures. An atlas of FDG uptake in this anatomic region was compiled on the basis of combined PET-CT findings in 11,000 patients. In general, patterns of FDG uptake were variable and often reflected patient activity during or immediately preceding the uptake phase. With the growing interest in PET-CT, interpreting radiologists and nuclear medicine physicians must be familiar with the patterns of FDG uptake in the head and neck to avoid misinterpretation or misdiagnosis. (c) RSNA, 2005.