Circulation of classical swine influenza virus in Europe between the wars?
Circulation of classical swine influenza virus in Europe between the wars?
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DOI：
10.1007/s00705-013-1950-x
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发表时间：
2013-12
影响因子：
2.7
通讯作者：
J. Lange;Marco Groth;Pumaree Kanrai;S. Pleschka;C. Scholtissek;R. Dürrwald;M. Platzer;A. Sauerbrei;R. Zell
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文献类型：
--
作者：
J. Lange;Marco Groth;Pumaree Kanrai;S. Pleschka;C. Scholtissek;R. Dürrwald;M. Platzer;A. Sauerbrei;R. Zell
对来自英国的两种猪流感病毒的全基因组进行了测序。系统发育分析揭示了经典的猪H1N1病毒，其中之一A/swine/伦敦与20世纪30年代早期的病毒株密切相关。这两种菌株也与最初由Richard Shope分离的菌株A/swine/爱荷华州/15/1930抗原相关。A/swine/伦敦的来源尚不清楚，但它与早期经典猪流感病毒的关系表明，这些病毒在欧洲的出现要早15-20年。
The complete genomes of two swine influenza viruses from England were sequenced. Phylogenetic analysis revealed classical swine H1N1 viruses, one of which, A/swine/London, is closely related to virus strains of the early 1930s. Both strains are also antigenically related to A/swine/Iowa/15/1930, the strain originally isolated by Richard Shope. The source of A/swine/London is unknown, but its relationship to early classical swine influenza viruses suggests that the emergence of these viruses in Europe has to be antedated by 15-20 years.