ASSOCIATION BETWEEN BIOCHEMICAL AND PHYSIOLOGICAL-PROPERTIES IN SINGLE MOTOR UNITS
ASSOCIATION BETWEEN BIOCHEMICAL AND PHYSIOLOGICAL-PROPERTIES IN SINGLE MOTOR UNITS
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DOI：
10.1002/mus.880110309
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发表时间：
1988-03-01
期刊：
影响因子：
3.4
通讯作者：
STUART, DG
中科院分区：
文献类型：
--
作者：
HAMM, TM;NEMETH, PM;STUART, DG
检查猫胫骨后肌的运动单位的生理和生化特性之间的关联。功能上孤立的运动单位根据其生理特性进行分类。随后对每个单位的单个肌纤维进行定量微生物化学分析，并使用糖原消耗方法在横截面中进行鉴定。苹果酸脱氢酶和β-羟酰基辅酶A脱氢酶的活性区分易疲劳（FF型）和耐疲劳（FR和S型）单位。快收缩单位中乳酸脱氢酶和腺苷激酶的活性均高于慢收缩单位。基于生理和生化特性或仅基于生化特性的聚类分析产生与 FF、FR 和 S 类型相同的分组。生理和生化特性之间的关联证实了生化上不同的运动单位组对应于生理上可识别的组的观点。
Motor units from the cat tibialis posterior muscle were examined for an association between physiological and biochemical properties. Functionally isolated motor units were categorized on the basis of their physiological properties. This was followed by quantitative microbiochemical analysis of single muscle fibers from each unit, identified in cross sections using the glycogen-depletion method. The activities of malate dehydrogenase and .beta.-hydroxyacyl-CoA dehydrogenase distinguished between fatigable (type FF) and fatigue-resistant (types FR and S) units. The activities of both lactate dehydrogenase and adenylokinase were higher in fast- than in slow-contracting units. Cluster analyses, based on both physiological and biochemical properties or on biochemical properties alone, produced groupings identical to types FF, FR, and S. The association between physiological and biochemical properties substantiates the idea that biochemically distinct groups of motor units correspond to physiologically identifiable groups.