Role of Lifestyle and Aging on the Longitudinal Change in Cardiorespiratory Fitness
Role of Lifestyle and Aging on the Longitudinal Change in Cardiorespiratory Fitness
复制标题
DOI：
10.1001/archinternmed.2009.312
复制
发表时间：
2009-10-26
影响因子：
--
通讯作者：
Blair, Steven N.
中科院分区：
文献类型：
--
作者：
Jackson, Andrew S.;Sui, Xuemei;Blair, Steven N.
背景：成年人的呼吸适应性（CRF）随年龄增长而下降，并受生活方式的影响。低CRF与疾病风险和老年人独立活动的能力有关。我们定义的纵向率随年龄增长和老龄化和生活方式与CRF.Methods：我们研究了一个队列的3429名妇女和16 889名男子，年龄在20至96岁，从有氧运动中心纵向研究谁完成了2至33个健康检查，从1974年至2006年。生活方式变量包括体重指数、自我报告的有氧运动和吸烟行为。结果：按性别分层的线性混合模型回归分析显示，CRF随年龄的下降不是线性的。45岁以后，CRF加速下降。体重指数每增加一个单位，女性CRF减少0.20代谢当量（MET）（95%置信区间，-0.21至-0.19）;男性CRF减少0.32 MET（-0.33至-0.20）。目前吸烟的男性和女性的CRF也较低（女性为-0.29 MET [95%置信区间，-0.40至-0.19]，男性为-0.41 MET [-0.44至-0.38]）。呼吸适应性与自我报告的体力activity.Conclusions呈正相关：男性和女性的呼吸适应性下降，在45岁后加速非线性速率。保持低BMI、身体活动和不吸烟与整个成年期的较高CRF相关。
Background: Cardiorespiratory fitness (CRF) in adults decreases with age and is influenced by lifestyle. Low CRF is associated with risk of diseases and the ability of older persons to function independently. We defined the longitudinal rate of CRF decline with aging and the association of aging and lifestyle with CRF.Methods: We studied a cohort of 3429 women and 16 889 men, aged 20 to 96 years, from the Aerobics Center Longitudinal Study who completed 2 to 33 health examinations from 1974 to 2006. The lifestyle variables were body mass index, self-reported aerobic exercise, and smoking behavior. Cardiorespiratory fitness was measured by a maximal Balke treadmill exercise test.Results: Linear mixed models regression analysis stratified by sex showed that the decline in CRF with age was not linear. After 45 years of age, CRF declined at an accelerated rate. For each unit of increase in body mass index, the CRF of women declined 0.20 metabolic equivalents (METs) (95% confidence interval, -0.21 to -0.19); that of men, 0.32METs(-0.33 to -0.20). Current smokers of both sexes also had lower CRF (-0.29 METs [95% confidence interval, -0.40 to -0.19] for women and -0.41 METS [-0.44 to -0.38] for men). Cardiorespiratory fitness was positively associated with self-reported physical activity.Conclusions: Cardiorespiratory fitness in men and women declines at a nonlinear rate that accelerates after 45 years of age. Maintaining a low BMI, being physically active, and not smoking are associated with higher CRF across the adult life span.