What Are the Major Causes of Dry Mouth in Elderly Adults?
What Are the Major Causes of Dry Mouth in Elderly Adults?
复制标题
老年人口干的主要原因是什么？
DOI：
10.1007/s40496-020-00262-6
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发表时间：
2020
影响因子：
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通讯作者：
Saito Ichiro
中科院分区：
文献类型：
--
作者：
Matsumoto Naoyuki;Ushikoshi-Nakayama Ryoko;Yamazaki Tomoe;Kaneko Mie;Saito Ichiro
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Purpose of ReviewThis article will review the etiology and mechanisms of onset of dry mouth in elderly adults.Recent FindingsSjögren syndrome (SS), a disease triggered by an autoimmune response against the exocrine glands, has long been recognized as a typical disease associated with such symptoms. Diabetes mellitus (DM) is also one of the causative diseases of dry mouth and results in oral mucosal inflammation. Previously, hyperglycemia induces dehydration and results dry mouth. Recently, hyperglycemia-induced insulin resistance impairs saliva secretion mechanisms and promotes dry mouth.SummaryAn increasing number of dry-mouth patients are presenting with complaints of generalized dryness. However, it can be presumed that a considerable number of patients have chronic oral inflammation due to dry mouth caused by something other than SS or DM.