Trends in fracture incidence: a population-based study over 20 years.
Trends in fracture incidence: a population-based study over 20 years.
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DOI：
10.1002/jbmr.2072
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发表时间：
2014-03
影响因子：
6.2
通讯作者：
Melton, L. Joseph, III
中科院分区：
文献类型：
--
作者：
Amin, Shreyasee;Achenbach, Sara J.;Atkinson, Elizabeth J.;Khosla, Sundeep;Melton, L. Joseph, III
为了评估所有骨骼部位各种原因骨折发生率的近期趋势，我们使用罗切斯特流行病学项目的综合（住院和门诊）数据资源，估计明尼苏达州奥姆斯特德县居民2009-11年的骨折发生率，并与1989-91年的类似数据进行比较。在2009年至2011年的三年研究期间，3549名≥ 50岁的居民经历了5244例单独骨折。经年龄和性别校正的（2010年美国白色人群）任何骨折的发生率为2704/100，000人-年（95% CI 2614-2793），所有骨折的发生率为4017/100，000（95% CI 3908-4127）。骨折的发生率随着年龄的增长而增加，但女性的年龄调整率高出49%。总体而言，1989- 1991年和2009-2011年之间，经统计学调整的骨折发生率增加了11%（从3627/10万人-年增加到4017/10万人-年; p = 0.008）。这主要是由于椎骨骨折的大幅增加（男女合计为+47%），这部分被女性髋部骨折的下降（-25%）所抵消。女性前臂远端骨折也减少了26%; 50岁及以上男性前臂远端骨折的增加没有统计学意义。在男性和女性中，尤其是在75岁以后，椎骨骨折的急剧增加部分归因于偶然诊断的椎骨骨折。然而，在大多数年龄组中观察到的髋部骨折发病率下降，继续保持了自1950年以来在该社区妇女中观察到的稳步下降趋势。更一般地说，这些数据表明，几十年前观察到的许多骨骼部位骨折发生率的急剧增加现在已经稳定下来。
To assess recent trends in fracture incidence from all causes at all skeletal sites, we used the comprehensive (inpatient and outpatient) data resources of the Rochester Epidemiology Project to estimate rates for Olmsted County, Minnesota, residents in 2009–11, compared to similar data from 1989–91. During the three-year study period, 2009–11, 3549 residents ≥ 50 years of age experienced 5244 separate fractures. The age- and sex-adjusted (to the 2010 United States white population) incidence of any fracture was 2704 per 100,000 person-years (95% CI 2614–2793) and that for all fractures was 4017 per 100,000 (95% CI 3908–4127). Fracture incidence increased with age in both sexes, but age-adjusted rates were 49% greater among the women. Overall, comparably adjusted fracture incidence rates increased by 11% (from 3627 to 4017 per 100,000 person-years; p = 0.008) between 1989–91 and 2009–2011. This was mainly due to a substantial increase in vertebral fractures (+47% for both sexes combined), which was partially offset by a decline in hip fractures (−25%) among the women. There was also a 26% reduction in distal forearm fractures among the women; an increase in distal forearm fractures among men age 50 years and over was not statistically significant. The dramatic increase in vertebral fractures, seen in both sexes and especially after age 75 years, was attributable in part to incidentally-diagnosed vertebral fractures. However, the fall in hip fracture incidence, observed in most age-groups, continues the steady decline observed among women in this community since 1950. More generally, these data indicate that the dramatic increases in the incidence of fractures at many skeletal sites that were observed decades ago have now stabilized.
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影响因子：
6.3
作者：
DONALDSON, LJ;COOK, A;THOMSON, RG
通讯作者：
THOMSON, RG
影响因子：
4
作者：
Kanis, J. A.;Johansson, H.;McCloskey, E. V.
通讯作者：
McCloskey, E. V.
影响因子：
4
作者：
Cooper, C.;Cole, Z. A.;Holroyd, C. R.;Earl, S. C.;Harvey, N. C.;Dennison, E. M.;Melton, L. J.;Cummings, S. R.;Kanis, J. A.
通讯作者：
Kanis, J. A.
影响因子：
4
作者：
Ettinger, B.;Black, D. M.;Dawson-Hughes, B.;Pressman, A. R.;Melton, L. J., III
通讯作者：
Melton, L. J., III
DOI：
10.1016/j.injury.2005.02.008
发表时间：
2005-11-01
影响因子：
2.5
作者：
Boufous, S;Finch, C;Close, J
通讯作者：
Close, J