THE EPIDEMIOLOGY OF GIANT-CELL ARTERITIS - REPORT OF A 10-YEAR STUDY IN SHELBY COUNTY, TENNESSEE

THE EPIDEMIOLOGY OF GIANT-CELL ARTERITIS - REPORT OF A 10-YEAR STUDY IN SHELBY COUNTY, TENNESSEE
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DOI:
10.1002/art.1780261007
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发表时间:
1983-01-01
影响因子:
--
通讯作者:
PINALS, RS
PINALS, RS
中科院分区:
其他
文献类型:
--
作者:
SMITH, CA;FIDLER, WJ;PINALS, RS

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巨细胞动脉炎(GCA)的流行病学研究在美国中南部的城市人口。1971年至1980年田纳西州谢尔比县GCA的发病率确定为总人口和年龄,性别和种族特定群体。在此期间,发现了26起案件。年平均发病率为0.35/10万。对于50岁以上的人,这一比例增加到1.58/100,000。白人的发病率是黑人的7倍,女性是男性的7倍。对患者的临床和实验室特征进行了审查,发现与其他人群相似。GCA在田纳西州谢尔比县的发生率远远低于其他进行过类似流行病学研究的地区。这种差异只能部分地由种族分布来解释。需要在南部地理区域进行类似的研究,以将研究结果放在透视图中,并指出可能在GCA中具有病因学意义的特定因素。
The epidemiology of giant cell arteritis (GCA) was studied in an urban population in the south central USA. The incidence of GCA in Shelby County, Tennessee for the years 1971 through 1980 was determined for the total population and for age-, sex-, and race-specific groups. Over this period 26 cases were identified. The average annual incidence was 0.35/100,000. This was increased to 1.58/100,000 for those over the age of 50. The incidence was 7 times greater in whites than in blacks and 7 times greater in females than in males. Clinical and laboratory features of the patients were reviewed and found to be similar to those in other populations. GCA is considerably less frequent in Shelby County, Tennessee than in other areas where similar epidemiologic studies have been performed. This difference can be accounted for only in part by racial distributions. Similar studies in southern geographic areas are needed to place the findings in perspective and point to specific factors which may have etiologic significance in GCA.