Bartonella spp. in Small Mammals, Benin
Bartonella spp. in Small Mammals, Benin
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DOI：
10.1089/vbz.2015.1838
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发表时间：
2016-04-01
影响因子：
2.1
通讯作者：
Foronda, Pilar
中科院分区：
文献类型：
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作者：
Martin-Alonso, Aaron;Houemenou, Gualbert;Foronda, Pilar
本研究旨在调查贝宁科托努地区小型哺乳动物体内巴尔通体的流行情况和遗传多样性。我们捕获了163只啮齿动物和12只食虫动物，并成功地从175只小型哺乳动物中的13只身上检测到巴尔通体DNA。检出与伊氏巴尔通体、摩擦巴尔通体和罗氏巴尔通体相同或相近的巴尔通体。在马氏假丝酵母的3个个体中发现了一个潜在的Bartonella新种，命名为Candidatus Bartonella mastomydis，其遗传学特征是以两个看家基因(rpoB和GLTA)和种间区为靶标。然而，20.8%的灰鼠被发现感染巴尔通体，分析的黑色鼠中没有一只呈阳性。从公共卫生的角度来看，这项工作可能是重要的，因为发现的巴尔通体具有人畜共患病的性质，并需要对这种新提出的巴尔通体的未知的人畜共患病潜力进行进一步的研究。
This study aimed to investigate the prevalence and genetic diversity of Bartonella organisms in small mammals in Cotonou, Benin. We captured 163 rodents and 12 insectivores and successfully detected Bartonella DNA from 13 of the 175 small mammal individuals. Bartonella spp., identical or closely related to Bartonella elizabethae, Bartonella tribocorum, and Bartonella rochalimae, was detected. A potential new Bartonella species, proposed as Candidatus Bartonella mastomydis, was found in three Mastomys individuals and genetically characterized by targeting two housekeeping genes (rpoB and gltA) and the intergenic species region. However, 20.8% of gray rats were found to be infected with Bartonella spp., and none of the black rats analyzed was positive. This work may be important from a public health point of view due to the zoonotic nature of the Bartonella species detected and warrants further investigation on the unknown zoonotic potential of this newly proposed Bartonella species.