Oxamides as novel NR2B selective NMDA receptor antagonists
Oxamides as novel NR2B selective NMDA receptor antagonists
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DOI：
10.1016/j.bmcl.2004.05.053
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发表时间：
2004-08-02
影响因子：
2.7
通讯作者：
Domány, G
中科院分区：
文献类型：
--
作者：
Barta-Szalai, G;Borza, I;Domány, G
从吲哚-2-甲酰胺衍生的一系列新的草酰胺被鉴定为有效的NR2B选择性NMDA受体拮抗剂。在小鼠福尔马林试验中，该组中的几个成员表现出良好的镇痛活性。(C)2004爱思唯尔有限公司。保留所有权利。
A novel series of oxamides derived from indole-2-carboxamides was identified as potent NR2B selective NMDA receptor antagonists. Several members of this group showed good analgesic activity in the mouse formalin test. (C) 2004 Elsevier Ltd. All rights reserved.