Fast determination of regional myocardial strain fields from tagged cardiac images using harmonic phase MRI
Fast determination of regional myocardial strain fields from tagged cardiac images using harmonic phase MRI
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DOI：
10.1161/01.cir.101.9.981
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发表时间：
2000-03-07
期刊：
影响因子：
37.8
通讯作者：
Lima, JAC
中科院分区：
文献类型：
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作者：
Garot, J;Bluemke, DA;Lima, JAC
由于缺乏快速分析技术，心脏的背景标记磁共振成像在临床上很难实现。我们研究了谐波相位(HARP)成像在快速定量心肌应变和详细分析多巴酚丁胺刺激下左心(LV)功能的准确性。方法对10名志愿者在静息状态和5~20微克(-1)时进行结果标记MRI检查。Kg(-1)。Min(-1)多巴酚丁胺，9例脑梗塞后患者静息。我们比较了常规技术和HARP评估的2D心肌应变(周向缩短，ECC；最大缩短，E-2；和E-2，方向)。使用HARP对数据进行完全定量分析的速度要快10倍。在合并资料中，各菌株的回归系数r=0.93(P
Background-Tagged MRI of the heart is difficult to implement clinically because of the lack of fast analytical techniques. We investigated the accuracy of harmonic phase (HARP) imaging for rapid quantification of myocardial strains and for detailed analysis of left ventricular (LV) function during dobutamine stimulation.Methods and Results-Tagged MRI was performed in 10 volunteers at rest and during 5 to 20 mu g(-1) . kg(-1) . min(-1) dobutamine and in 9 postinfarct patients at rest. We compared 2D myocardial strains (circumferential shortening, Ecc; maximal shortening, E-2; and E-2, direction) as assessed by a conventional technique and by HARP. Full quantitative analysis of the data was 10 times faster with HARP. For pooled data, the regression coefficient was r=0.93 for each strain (P