Clinical tests: sensitivity and specificity
Clinical tests: sensitivity and specificity
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DOI：
10.1093/bjaceaccp/mkn041
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发表时间：
2008-12-01
期刊：
影响因子：
1.6
通讯作者：
McCluskey, Anthony
中科院分区：
文献类型：
--
作者：
Lalkhen, Abdul Ghaaliq;McCluskey, Anthony
许多临床测试被用来确认或反驳疾病的存在或进一步的诊断过程。理想情况下，这样的测试正确地识别出所有患有这种疾病的患者，并同样正确地识别出所有没有疾病的患者。换句话说，完美的检测在没有疾病的患者身上永远不会是阳性的，在实际上有疾病的患者身上永远不会是阴性的。大多数临床试验都达不到这一理想。
Many clinical tests are used to confirm or refute the presence of a disease or further the diagnostic process. Ideally such tests correctly identify all patients with the disease, and similarly correctly identify all patients who are disease free. In other words, a perfect test is never positive in a patient who is disease free and is never negative in a patient who is in fact diseased. Most clinical tests fall short of this ideal.