The Prognostic Implications of Bone Invasion in Gingival Squamous Cell Carcinoma
The Prognostic Implications of Bone Invasion in Gingival Squamous Cell Carcinoma
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DOI：
10.21873/anticanres.12309
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发表时间：
2018-02-01
影响因子：
2
通讯作者：
Sasaki, Akira
中科院分区：
文献类型：
--
作者：
Yoshida, Shoko;Shimo, Tsuyoshi;Sasaki, Akira
背景/目的：本研究旨在评估牙龈鳞状细胞癌（SCC）的骨浸润与临床病理表现之间的关系，并旨在确定骨浸润是否是牙龈SCC的独立预后因素。患者和方法：本研究回顾性分析了78例接受手术治疗的牙龈鳞状细胞癌患者。骨侵犯程度按病理学分为髓性、皮质性和无骨侵犯。结果：29例患者出现皮质骨侵犯，22例患者出现髓质骨侵犯。髓骨侵犯与肿瘤大小（p=0.017）、病理N分类（p= 0.001）、肿瘤大小（p= 0.0001）、肿瘤大小（p = 0.00
Background/Aim: This study evaluated the associations between bone invasion of gingival squamous cell carcinoma (SCC) and clinicopathological manifestations, and aimed to determine whether bone invasion is an independent prognostic factor in gingival SCC. Patients and Methods: The study was a retrospective review of 78 patients with gingival SCC who underwent surgery with curative intent. The level of bone invasion was pathologically categorized as medullary, cortical or no bone invasion. Results: Cortical and medullary bone invasion was present in 29 and 22 patients, respectively. There was a significant association between medullary bone invasion and tumor size (p=0.017), pathological N classification (p