PULVINAR NUCLEI OF THE BEHAVING RHESUS-MONKEY - VISUAL RESPONSES AND THEIR MODULATION
PULVINAR NUCLEI OF THE BEHAVING RHESUS-MONKEY - VISUAL RESPONSES AND THEIR MODULATION
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DOI：
10.1152/jn.1985.54.4.867
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发表时间：
1985-01-01
影响因子：
2.5
通讯作者：
KEYS, W
中科院分区：
文献类型：
--
作者：
PETERSEN, SE;ROBINSON, DL;KEYS, W
我们已经研究了警觉，训练有素的恒河猴枕的三个分区的神经元的属性：1）下，视网膜定位映射区（PI），2）外侧，视网膜定位组织区（PL），和3）背内侧视觉部分的外侧枕（Pdm），其中有一个粗糙的视网膜定位组织。我们测试了神经元对静止和运动刺激的视觉反应，以及行为操纵产生的这些反应的变化。所有区域都包含对刺激方向敏感的细胞以及对刺激运动方向有选择性的神经元;然而，所有三个区域中的大多数细胞对这些属性都是广泛调谐或非选择性的。几乎所有的细胞都对刺激的开始做出反应，相当数量的细胞也对刺激的终止做出反应，很少有细胞只做出反应。几乎所有的细胞都增加了对视觉刺激的放电率。在两个retinotopically映射的区域，PI和PL的感受野，有明确的边界。这些感受野的大小与感受野的偏心率呈正相关。其余区域Pdm的感受野通常非常大，但排除这些大的感受野后，表现出与偏心率类似的相关性。所有测试的枕细胞（n = 20）在视网膜坐标中映射;感受野相对于视网膜定位。我们没有发现具有凝视门控特征的细胞（2），也没有在空间坐标系中映射的细胞。PI和PL中的响应时间比Pdm中的时间短且变化小。积极使用刺激物可以增强或减弱视觉反应。眼动调制被发现在所有三个细分在大约相等的频率。注意调制在Pdm中常见，在PI和PL中罕见。调制是空间选择性的Pdm和非选择性PI为少数测试细胞。这些数据表明，PDM和其他两个领域之间的功能差异，并建议，PDM起着选择性视觉注意的作用，而PI和PL可能有助于其他方面的视觉感知。
We have examined the properties of neurons in three subdivisions of the pulvinar of alert, trained rhesus monkeys 1) an inferior, retinotopically mapped area (PI), 2) a lateral, retinotopically organized region (PL), and 3) a dorsomedial visual portion of the lateral pulvinar (Pdm), which has a crude retinotopic organization. We tested the neurons for visual responses to stationary and moving stimuli and for changes in these responses produced by behavioral manipulations. All areas contain cells sensitive to stimulus orientation as well as neurons selective for the direction of stimulus movement; however, the majority of cells in all three regions are either broadly tuned or nonselective for these attributes. Nearly all cells respond to stimulus onset, a significant number also give a response to stimulus termination, and rarely a cell gives only off responses. Nearly all cells increase their discharge rate to visual stimuli. Receptive fields in the two retinotopically mapped regions, PI and PL, have well-defined borders. The sizes of these receptive fields show a positive correlation with the eccentricity of the receptive fields. The receptive fields in the remaining region, Pdm, are frequently very large, but with these large fields excluded, show a similar correlation with eccentricity. All pulvinar cells tested (n = 20) were mapped in retinal coordinates; the receptive fields are positioned in relation to the retina. We found no cells with gaze-gated characteristics (2), nor cells mapped in a spatial coordinate system. The response latencies in PI and PL are shorter and less variable than the latencies in Pdm. Active use of a stimulus can produce an enhancement or attenuation of the visual response. Eye-movement modulation was found in all three subdivisions in about equal frequencies. Attentional modulation was common in Pdm and was rare in PI and PL. The modulation is spatially selective in Pdm and nonselective in PI for a small number of tested cells. These data demonstrate functional differences between Pdm and the other two areas and suggest that Pdm plays a role in selective visual attention, whereas PI and PL probably contribute to other aspects of visual perception.