Dietary iron intakes based on food composition data may underestimate the contribution of potentially exchangeable contaminant iron from soil
Dietary iron intakes based on food composition data may underestimate the contribution of potentially exchangeable contaminant iron from soil
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DOI：
10.1016/j.jfca.2014.11.016
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发表时间：
2015-06-01
影响因子：
4.3
通讯作者：
Siyame, Edwin W. P.
中科院分区：
文献类型：
--
作者：
Gibson, Rosalind S.;Wawer, Anna A.;Siyame, Edwin W. P.
从一天称重记录计算的铁摄入量进行了比较，从同一天分析的重复的饮食复合材料收集120马拉维妇女生活在两个农村地区，对比土壤矿物学和土壤铁可能污染谷物。土壤和饮食复合材料从两个地区，然后进行模拟的胃肠道消化和铁的利用率，测量使用Caco-2细胞模型。Zombwe（16.6 vs. 10.1 mg/d）和Mikalango（29.6 vs. 19.1 mg/d）的分析铁摄入量中位数（mg/d）均高于（p < 0.001）计算摄入量，这归因于基于饮食复合物中高Al和Ti浓度的一些土壤污染铁。来自Zombwe的酸性土壤中的一小部分铁，而不是Mikalango石灰质土壤，是生物可利用的，因为它诱导了细胞中的铁蛋白表达，并且可能导致了更高的血浆铁蛋白和全身铁对于Zombwe妇女来说，尽管铁摄入量较低。总之，从食物组成数据计算的铁摄入量被低估了，强调了分析重复饮食组合物的重要性，其中可能存在来自土壤的外来污染物铁。酸性污染物土壤可能对铁营养有很小但有用的贡献。(C)2015作者爱思唯尔公司出版
Iron intakes calculated from one-day weighed records were compared with those from same day analyzed duplicate diet composites collected from 120 Malawian women living in two rural districts with contrasting soil mineralogy and where threshing may contaminate cereals with soil iron. Soils and diet composites from the two districts were then subjected to a simulated gastrointestinal digestion and iron availability in the digests measured using a Caco-2 cell model. Median analyzed iron intakes (mg/d) were higher (p < 0.001) than calculated intakes in both Zombwe (16.6 vs. 10.1 mg/d) and Mikalango (29.6 vs. 19.1 mg/d), attributed to some soil contaminant iron based on high Al and Ti concentrations in diet composites. A small portion of iron in acidic soil from Zombwe, but not Mikalango calcareous soil, was bioavailable, as it induced ferritin expression in the cells, and may have contributed to higher plasma ferritin and total body iron for the Zombwe women reported earlier, despite lower iron intakes. In conclusion, iron intakes calculated from food composition data were underestimated, highlighting the importance of analyzing duplicate diet composites where extraneous contaminant iron from soil is likely. Acidic contaminant soil may make a small but useful contribution to iron nutrition. (C) 2015 The Authors. Published by Elsevier Inc.