Synaptic organization of the nucleus dorsolateralis anterior thalami in the Japanese quail (Coturnix coturnix japonica)
Synaptic organization of the nucleus dorsolateralis anterior thalami in the Japanese quail (Coturnix coturnix japonica)
复制标题
日本鹌鹑（Coturnix coturnix japonica）丘脑背外侧核的突触组织
DOI：
10.1016/0006-8993(87)91412-0
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发表时间：
1987
期刊：
影响因子：
2.9
通讯作者：
M. Watanabe
中科院分区：
文献类型：
--
作者：
M. Watanabe
鸟类的丘脑背外侧前核（DLA）是哺乳动物背外侧膝状体核的同源物6，16。用光镜和电镜技术研究了日本鹌鹑DLA中确定的中继神经元在视网膜和视觉Wulst终末的位置。将辣根过氧化物酶（HRP）注入视觉Wulst，发现投射同侧或对侧的中继神经元位于DLA的头外侧亚区（DLAlr）和外侧亚区（DLL）的A区和B区。切除对侧眼导致DLAlr中的致密终末变性和A区和B中的中度终末变性。相比之下，视觉Wulst的病变在DLL的A区和B区产生密集的变性终末。HRP注入视觉Wulst或视神经后，分别在电镜下观察到DLA中的中继神经元或视网膜终末的胞体和近端树突。来自视网膜的终末含有球形囊泡、糖原颗粒和具有宽间隔嵴的线粒体。来自视网膜的末梢与HRP标记的中继神经元的近端树突和胞体进行突触接触。突触前树突与中继神经元的树突形成对称的突触接触。在DLAlr中观察到突触小球，其涉及中继神经元的树突、来自视网膜的终末和突触前树突。视觉Wulst的病变导致具有球形囊泡的小终末变性。这些终末不参与DLA的突触小球，但与不明神经元的棘和突触前树突的终末进行不对称接触。
The nucleus dorsolateralis anterior thalami (DLA) of birds is the homologue of the mammalian dorsal lateral geniculate nucleus6,16. The positions of terminals from the retina and visual Wulst upon identified relay neurons in the DLA were examined in Japanese quail with both light and electron microscopic techniques. Injection of horseradish peroxidase (HRP) into the visual Wulst showed that relay neurons projecting ipsilaterally or contralaterally were located in a rostrolateral subdivision (DLAlr) and in Zones A and B of a lateral subdivision (DLL) of the DLA. Removal of the contralateral eye resulted in dense terminal degeneration in the DLAlr and moderate terminal degeneration in Zones A and B. By contrast, lesions in the visual Wulst produced dense degenerating terminals in Zones A and B of the DLL. The somata and proximal dendrites of relay neurons or terminals from the retina in the DLA were identified electron microscopically following HRP injection into the visual Wulst or optic nerve, respectively. Terminals from the retina contained spherical vesicles, glycogen granules, and mitochondria with widely spaced cristae. Terminals from the retina made synaptic contact with proximal dendrites and somata of HRP-labeled relay neurons. Presynaptic dendrites formed symmetric synaptic contact with dendrites of relay neurons. Synaptic glomeruli were observed in the DLAlr that involved dendrites of relay neurons, terminals from the retina and presynaptic dendrites. Lesions of the visual Wulst resulted in degeneration of small terminals with spherical vesicles. These terminals were not involved in the synaptic glomeruli of the DLA, but made asymmetric contacts with spine of unidentified neurons and with terminals of presynaptic dendrites.