A multi-wavelength (u.v. to visible) laser system for early detection of oral cancer

A multi-wavelength (u.v. to visible) laser system for early detection of oral cancer
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用于早期检测口腔癌的多波长(紫外线到可见光)激光系统

DOI:
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发表时间:
2015
期刊:
Biomedical optics
影响因子:
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通讯作者:
W. Mimnagh
W. Mimnagh
中科院分区:
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文献类型:
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作者:
S. Najda;P. Perlin;M. Leszczynski;T. Slight;W. Meredith;M. Schemmann;H. Moseley;J. A. Woods;R. Valentine;S. Kalra;P. Mossey;E. Theaker;M. Macluskey;G. Mimnagh;W. Mimnagh

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介绍了一种基于GaN半导体激光器技术的多波长(360 nm-440 nm)实时光子癌症检测器(PCD)光学系统。使用蓝色激光技术进行癌症早期检测的概念验证已经在食管癌中进行了测试和验证。这个概念被扩展到考虑更宽的波长范围,PCD最初将用于口腔癌的早期诊断。PCD创建口腔图像(宽场白色光检测),并使用窄场可调检测器以高灵敏度在口腔内映射任何可疑病变。
A multi-wavelength (360nm – 440nm), real-time Photonic Cancer Detector (PCD) optical system based on GaN semiconductor laser technology is outlined. A proof of concept using blue laser technology for early detection of cancer has already been tested and proven for esophageal cancer. This concept is expanded to consider a wider range of wavelengths and the PCD will initially be used for early diagnosis of oral cancers. The PCD creates an image of the oral cavity (broad field white light detection) and maps within the oral cavity any suspicious lesions with high sensitivity using a narrow field tunable detector.