Right Ventricular Systolic Dysfunction in Young Adults Born Preterm
Right Ventricular Systolic Dysfunction in Young Adults Born Preterm
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DOI：
10.1161/circulationaha.113.002583
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发表时间：
2013-08-13
期刊：
影响因子：
37.8
通讯作者：
Leeson, Paul
中科院分区：
文献类型：
--
作者：
Lewandowski, Adam J.;Bradlow, William M.;Leeson, Paul
Background-Young adults born preterm have distinct differences in left ventricular mass, function, and geometry. Animal studies suggest that cardiomyocyte changes are evident in both ventricles after preterm birth; therefore, we investigated whether these young adults also have differences in their right ventricular structure and function.Methods and Results-We studied 102 preterm-born young adults followed up prospectively since birth and 132 term-born control subjects born to uncomplicated pregnancies. We quantified right ventricular structure and function by cardiovascular magnetic resonance on a 1.5-T Siemens scanner using Argus and TomTec postprocessing software. Preterm birth was associated with a small right ventricle (end diastolic volume, 79.8 +/- 13.2 versus 88.5 +/- 11.8 mL/m(2); P
