EFFECTS OF ENVIRONMENTAL ENRICHMENT AND IMPOVERISHMENT ON RAT CEREBRAL-CORTEX
EFFECTS OF ENVIRONMENTAL ENRICHMENT AND IMPOVERISHMENT ON RAT CEREBRAL-CORTEX
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DOI：
10.1002/neu.480030105
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发表时间：
1972-01-01
期刊：
影响因子：
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通讯作者：
ROSENZWEIG, MR
中科院分区：
文献类型：
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作者：
DIAMOND, MC;LINDNER, B;ROSENZWEIG, MR
本文的第一部分论述了大鼠脑解剖学的影响变化的起始年龄和暴露于丰富（复杂）或贫困（限制）的环境条件的持续时间。比较大脑皮质深度测量和大脑样品的重量。本报告的第二部分涉及试图确定富集条件或改善条件对组织学脑变化的影响程度;这是通过与标准群体环境中动物的脑进行比较来完成的。结果表明，更大和更广泛的皮层深度的影响被发现在大鼠暴露30天，而不是80天，以各自的环境。在背侧皮质段中富集效应更为突出，而在外侧皮质段中富集效应更为明显。通过测量多个节段的深度，而不是通过测量相对大块组织的重量，可以获得更精确的皮质变化定位。
The first part of this paper deals with rat brain anatomy as affected by variations of starting age and of duration of exposure to enriched (complex) or impoverished (restricted) environmental conditions. Cerebral cortical depth measurements and weights of brain samples are compared. The second part of this report is concerned with an attempt to establish the extent to which the enriched condition or the improverished condition is responsible for the histological brain changes; this is done by comparison with brains from animals in the standard colony environment. The results indicate that both larger and more extensive cortical depth effects are found in rats exposed for 30 days rather than 80 days to their respective environments. The effects of enrichment are more prominent in the dorsal cortical segments, whereas the effects of impoverishment are more evident in the lateral cortical segments. More precise localization of cortical changes is obtained by measuring the depths at many segments than by taking the weights of relatively large blocks of tissue.