Higher New York Heart Association classes and increased mortality and hospitalization in patients with heart failure and preserved left ventricular function
Higher New York Heart Association classes and increased mortality and hospitalization in patients with heart failure and preserved left ventricular function
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DOI：
10.1016/j.ahj.2005.03.066
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发表时间：
2006-02-01
影响因子：
4.8
通讯作者：
Fleg, JL
中科院分区：
文献类型：
--
作者：
Ahmed, A;Aronow, WS;Fleg, JL
背景纽约心脏协会(NYHA)分级与心力衰竭住院患者预后的关系尚不清楚。方法我们对988名参与DIG试验的心力衰竭患者进行了回顾性随访研究。使用COX比例风险模型，我们估计了风险和全因死亡率、心力衰竭死亡率、全因住院以及在38.5个月的中位随访期间因心力衰竭恶化而住院的风险。结果患者的中位年龄为68岁；41.2%为女性，13.9%为非白人。总体而言，23.4%的患者死亡，19.9%的患者因心力衰竭恶化而住院。NYHA分级I、II、III、IV级患者的比例分别为19.9%、58.0%、20.9%、1.2%，全死因死亡率分别为14.7%、21.1%、35.9%、58.3%(P
Background The association between New York Heart Association (NYHA) class and outcomes inpatients with heart failure and preserved systolic function is not well known.Methods We performed a retrospective follow-up study of 988 patients with heart failure with ejection fraction > 45% who participated in the DIG trial. Using Cox proportional hazard models, we estimated risks and all-cause mortality, heart failure mortality, all-cause hospitalization, and hospitalization due to worsening heart failure during a median follow-up of 38.5 months.Results Patients had a median age of 68 years; 41.2% were women and 13.9%, nonwhites. Overall, 23.4% of patients died, and 19.9% were hospitalized because of worsening heart failure. Proportion of patients with NYHA classes I, II, III, and IV were 19.9%, 58.0%, 20.9%, and 1.2%, respectively, and 14.7%, 21.1%, 35.9%, and 58.3%, respectively, died of all causes ( P