SARS-CoV-2 Infection Leads to Neurological Dysfunction
SARS-CoV-2 Infection Leads to Neurological Dysfunction
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DOI：
10.1007/s11481-020-09924-9
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发表时间：
2020-05-23
影响因子：
6.2
通讯作者：
Byrareddy, Siddappa N.
中科院分区：
文献类型：
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作者：
Acharya, Arpan;Kevadiya, Bhavesh D.;Byrareddy, Siddappa N.
在感染严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)后，出现了一些神经系统疾病并发症。虽然大多数新冠肺炎呼吸道疾病患者都会出现头痛、恶心和呕吐，但高达40%的患者也会出现头晕、神志不清、脑血管疾病、肌肉疼痛、共济失调和癫痫发作。味觉和嗅觉丧失、视力缺陷和疼痛同时发生。这种与实验室确认的SARS-CoV-2感染有关的中枢神经系统(CNS)体征和症状通常会危及生命。目前正在评估有神经系统症状的患者的医疗保健提供者在任何鉴别诊断中都需要考虑新冠肺炎。这些考虑将有助于迅速检测、隔离和预防病毒传播，加速最佳临床结果。
A number of neurological disease complications have been seen following infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While most person with COVID-19 respiratory disease demonstrate headache, nausea and vomiting, up to 40% present also experience dizziness, confusion, cerebrovascular disease, muscle pain, ataxia and seizures. Loss of taste and smell, defects in visual acuity and pain occur in parallel. Such central nervous system (CNS) signs and symptoms linked to laboratory-confirmed SARS-CoV-2 infection is often life threatening. Health care providers currently evaluating patients with neurologic symptoms need consider COVID-19 in any differential diagnosis. These considerations will facilitate prompt testing, isolation and prevention of viral transmission speeding best clinical outcomes.