Extraintestinal pathogenic Escherichia coli:: "The other bad E coli"
Extraintestinal pathogenic Escherichia coli:: "The other bad E coli"
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DOI：
10.1067/mlc.2002.121550
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发表时间：
2002-03-01
期刊：
影响因子：
--
通讯作者：
Russo, TA
中科院分区：
文献类型：
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作者：
Johnson, JR;Russo, TA
肠外致病性大肠杆菌（ExPEC），大肠杆菌的特殊菌株，导致大多数肠外大肠杆菌感染，代表了一个主要的，但很少受到重视的健康威胁。虽然它们进化的原因仍然是神秘的，但由于它们的许多毒力特性，ExPEC显然具有在宿主肠道外引起疾病的独特能力。更广泛地了解ExPEC的存在和重要性，并更好地了解其独特的毒力机制，水库和传播途径，可能会导致有效的预防性干预措施，对病态和昂贵的感染ExPEC的原因。
Extraintestinal pathogenic Escherichia coli (ExPEC), the specialized strains of E coli that cause most extraintestinal E coli infections, represent a major but little-appreciated health threat. Although the reasons for their evolution remain mysterious, by virtue of their numerous virulence traits ExPEC clearly possess a unique ability to cause disease outside the host intestinal tract. Broader appreciation of the existence and importance of ExPEC and better understandings of their distinctive virulence mechanisms, reservoirs, and transmission pathways may lead to effective preventive interventions against the morbid and costly infections ExPEC cause.