The effects of smoking on neutrophil/lymphocyte, platelet//lymphocyte ratios
The effects of smoking on neutrophil/lymphocyte, platelet//lymphocyte ratios
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DOI：
10.4149/bll_2018_023
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发表时间：
2018-01-01
影响因子：
1.5
通讯作者：
Eryilmaz, M. A.
中科院分区：
文献类型：
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作者：
Gumus, F.;Solak, I;Eryilmaz, M. A.
目的：比较吸烟者和非吸烟者中性粒细胞/淋巴细胞比率(NLR)、血小板/淋巴细胞比率(PLR)和平均血小板体积/血小板比率(MPV/Plt)。记录所有患者的社会人口学数据和血液学参数。结果：病例组平均年龄为35.88±10.56岁，对照组平均年龄为38.97±10.56岁。吸烟者中男性占80%(n=160)，女性占20%(n=40)。对照组男性占27.5%(n=55)，女性占72.5%(n=145)。吸烟组NLR和MPV/Plt比值明显高于吸烟组(p<；0.05)。非吸烟组PLR显著高于非吸烟组(P<；0.05)。结论：作为全身炎症标志物的NLR增加，PLR降低，MPV/Plt比值升高，提示血栓栓塞症的风险。
OBJECTIVE: The aim of this study was to compare the Neutrophil to Lymphocyte ratio (NLR), Platelet to Lymphocyte ratio (PLR) and Mean Platelet Volume to Platelet (MPV/Plt) ratio of smokers and non-smokers.METHODS: Two hundred smokers and two hundred non-smoking healthy volunteers were enrolled in this study. Sociodemographic data and hematologic parameters of all patients were recorded. NLR, PLR and MPV/Plt ratios were calculated.RESULTS: The mean age of the case group was 35.88 +/- 10.56 and the mean age of the control group was 38.97 +/- 10.56. 80 % (n = 160) of the smokers were male and 20 % (n = 40) were female. 27.5 % (n = 55) of the control group were male and 72.5 % (n = 145) were female. The smoker group had higher NLR and MPV/Plt ratio (p < 0.05). PLR was significantly higher for the non-smoker group (p < 0.05).CONCLUSION: As a result of our study, an increase in the NLR which is used as a systemic inflammatory marker, a decrease in the PLR and an increase in the MPV/Plt ratio which indicates thromboembolism risk were found for the smoker group.