Venous Thromboembolism in Korean Patients Undergoing Major Orthopedic Surgery: A Prospective Observational Study using Computed Tomographic (CT) Pulmonary Angiography and Indirect CT Venography
Venous Thromboembolism in Korean Patients Undergoing Major Orthopedic Surgery: A Prospective Observational Study using Computed Tomographic (CT) Pulmonary Angiography and Indirect CT Venography
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DOI：
10.3346/jkms.2010.25.1.28
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发表时间：
2010-01-01
影响因子：
4.5
通讯作者：
Kim, Shin-Yoon
中科院分区：
文献类型：
--
作者：
Cha, Seung-Ick;Lee, Shin-Yeop;Kim, Shin-Yoon
在接受大型骨科手术的患者中，计算机断层扫描（CT）肺血管造影和间接CT静脉造影（CTPA-CTV）研究缺乏深静脉血栓（DVT）和肺栓塞（PE）的数据。对 363 名接受大型骨科手术的韩国患者进行了一项前瞻性观察研究，以确定静脉血栓栓塞 (VTE)，特别是近端 DVT 和 PE 的发生率。 VTE 的发生率为 16.3% (n=59)。其中，8名患者（2.2%）出现症状。接受全膝关节置换术的患者中 VTE 发生率最高 (40.4%)，其次是髋部骨折手术 (16.4%) 和全髋关节置换术 (8.7%)；P=65 岁是接受大型骨科手术的患者发生近端 DVT 或 PE 的显着危险因素（比值比 [OR]，2.4；95% 置信区间 [CI]，1.1-5.1；P=0.025；OR， 2.1；95% CI，1.0-4.4；P=0.046，两者合计，PE 的总体发生率为 6.6%，有症状的 PE 发生率为 1.1%，年龄 >= 65 岁是近端 DVT 或 PE 的重要危险因素。
In patients undergoing major orthopedic surgery, data of deep venous thrombosis (DVT) and pulmonary embolism (PE) are lacking as studied by computed tomographic (CT) pulmonary angiography and indirect CT venography (CTPA-CTV). A prospective observational study was performed for 363 Korean patients undergoing major orthopedic surgery to determine the incidence of venous thromboembolism (VTE), especially proximal DVT and PE. The incidence of VTE was 16.3% (n=59). Of them, 8 patients (2.2%) were symptomatic. The rate of VTE was the highest in patients who underwent total knee replacement (40.4%), followed by hip fracture surgery (16.4%), and total hip replacement (8.7%; P= 65 yr were significant risk factors for proximal DVT or PE in patients undergoing major orthopedic surgery (odds ratio [OR], 2.4; 95% confidence interval [CI], 1.1-5.1; P=0.025; and OR, 2.1; 95% CI, 1.0-4.4; P=0.046, respectively). Taken together, the overall incidence of PE was 6.6% and rate of symptomatic PE rate was 1.1%. Knee joint replacement and age >= 65 yr were significant risk factors for proximal DVT or PE.