Familial aggregation absolute pitch
Familial aggregation absolute pitch
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DOI：
10.1086/303057
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发表时间：
2000-09-01
影响因子：
9.8
通讯作者：
Freimer, NB
中科院分区：
文献类型：
--
作者：
Baharloo, S;Service, SK;Freimer, NB
绝对音高(AP)是一种行为特征，它被定义为在没有参考音高的情况下识别音调的能力。AP是研究复杂人类行为发育过程中基因和环境相互作用的理想表型。在正式的音高感知听觉测试中得分特别高的人被指定为“AP-1”。如本报告所述，对AP-1先证者的兄弟姐妹和对照样本的听觉测试表明，AP-1在家族中聚集。讨论了这一发现对AP-1易感基因定位的意义。
Absolute pitch (AP) is a behavioral trait that is defined as the ability to identify the pitch of tones in the absence of a reference pitch. AP is an ideal phenotype for investigation of gene and environment interactions in the development of complex human behaviors. Individuals who score exceptionally well on formalized auditory tests of pitch perception are designated as "AP-1." As described in this report, auditory testing of siblings of AP-1 probands and of a control sample indicates that AP-1 aggregates in families. The implications of this finding for the mapping of loci for AP-1 predisposition are discussed.