Shore crabs reveal novel evolutionary attributes of the mushroom body.
Shore crabs reveal novel evolutionary attributes of the mushroom body.
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DOI：
10.7554/elife.65167
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发表时间：
2021-02-09
期刊：
影响因子：
7.7
通讯作者：
Sayre ME
中科院分区：
文献类型：
--
作者：
Strausfeld N;Sayre ME
蘑菇体的神经组织在很大程度上是一致的昆虫，而祖先的地面模式分歧广泛跨甲壳类动物谱系导致连续损失的列和收购圆顶中心保留祖先赫布样网络和aminergic连接。我们在这里展示了一个重大的背离这一进化趋势的Brachyura，最近的软介类血统。在海岸Hemigrapsus nudus中，蘑菇体萼不是占据外侧前脑的嘴侧表面，而是深埋在其中，它们的柱向外延伸到大脑表面上的一个广阔的脑回系统。蘑菇体神经元之间的组织在其组成的神经细胞中达到了极端的精细化。肾盏、脑柱，尤其是脑回显示出DC 0免疫反应性，这是参与学习和记忆的广泛回路的指示器。
Neural organization of mushroom bodies is largely consistent across insects, whereas the ancestral ground pattern diverges broadly across crustacean lineages resulting in successive loss of columns and the acquisition of domed centers retaining ancestral Hebbian-like networks and aminergic connections. We demonstrate here a major departure from this evolutionary trend in Brachyura, the most recent malacostracan lineage. In the shore crab Hemigrapsus nudus, instead of occupying the rostral surface of the lateral protocerebrum, mushroom body calyces are buried deep within it with their columns extending outwards to an expansive system of gyri on the brain’s surface. The organization amongst mushroom body neurons reaches extreme elaboration throughout its constituent neuropils. The calyces, columns, and especially the gyri show DC0 immunoreactivity, an indicator of extensive circuits involved in learning and memory.