New population-based references for birth weight, length, and head circumference in singletons and twins from 23 to 43 gestation weeks
New population-based references for birth weight, length, and head circumference in singletons and twins from 23 to 43 gestation weeks
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DOI：
10.3109/07853890.2013.803739
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发表时间：
2013-09-01
影响因子：
4.4
通讯作者：
Dunkel, Leo
中科院分区：
文献类型：
--
作者：
Sankilampi, Ulla;Hannila, Marja-Leena;Dunkel, Leo
背景和目标。临床和流行病学研究需要出生人数曲线。我们构建了出生体重（BW）、长度（BL）和头围（BHC）参考，评估了双胞胎和胎次的影响，并定义了胎龄小、合适和大的分界点。材料和方法。对1996-2008年在芬兰出生的所有753,036名婴儿的出生登记数据进行了清理，以创建反映最佳宫内生长的参考资料。最终数据包括533,666例单胎和15,033例双胞胎（中位妊娠周（gws）分别为40.0和37.1，其中41.6%为初产）。针对初产或多产母亲所生的单胎和双胞胎，分别构建了性别特异性的体重、BL和BHC参考文献，从23至43 gws。采用GAMLSS方法进行建模。在36吉瓦以后的单例中，与1979-1983年的先前参考相比，观察到体重和体重增加。从30吉瓦开始，双胞胎就从单胎分化出来了。在37.0 gws时，平均体重比单胎低400 g，平均身高比单胎短1.2 cm。从30 gws开始，多胎婴儿的出生尺寸大于初产母亲。以人口为基础的出生规模参考资料可用于评估出生规模。考虑胎数和胎次可以提高出生尺寸评估的准确性。
Background and objectives. Birth size curves are needed for clinical and epidemiological purposes. We constructed birth weight (BW), length (BL), and head circumference (BHC) references, assessed effects of twinness and parity, and defined cut-off points for small, appropriate, and large for gestational age.Materials and methods. Birth register data of all 753,036 infants born in 1996-2008 in Finland were cleaned to create references reflecting optimal intrauterine growth. The final data included 533,666 singletons and 15,033 twins (median gestation weeks (gws) 40.0 and 37.1, respectively, 41.6% primiparous). Sex-specific BW, BL, and BHC references were constructed from 23 to 43 gws separately for singletons and twins born to primiparous or multiparous mothers. GAMLSS method was used for modelling.Results. In singletons from 36 gws onwards, increased BW and BL were observed in comparison to previous reference from 1979-1983. Twins diverged from singletons from 30 gws onwards. At 37.0 gws, mean BW was 400 g lower and mean BL 1.2 cm shorter than in singletons. From 30 gws onwards, birth size was larger in infants of multiparous than primiparous mothers.Conclusions. Population-based birth size references are available for the evaluation of birth size. Accounting for plurality and parity improves the accuracy of birth size evaluation.