Prevalence of and risk factors for atrial fibrillation in Korean adults older than 40 years

Prevalence of and risk factors for atrial fibrillation in Korean adults older than 40 years
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DOI:
10.3346/jkms.2005.20.1.26
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发表时间:
2005-02-01
影响因子:
4.5
通讯作者:
Jeong, JH
Jeong, JH
中科院分区:
医学4区
文献类型:
--
作者:
Jeong, JH

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心房颤动(AF)是一种常见的心律失常,是脑卒中的独立危险因素.房颤的发病率随着年龄的增长而增加,大多数受影响的人都有潜在的心脏疾病。本研究旨在描述韩国人房颤的患病率和危险因素。在这项研究中,14,540名40岁以上的成年人(男性6,573人/女性7,967人)在2000年4月至2000年12月期间接受了一般健康筛查。参与者回答问卷并接受包括血压、心电图(ECG)、总胆固醇和空腹血糖在内的检查。数据分析采用SPSS10.0forWindows软件包。40岁以上人群的房颤患病率为0.7%,65岁以上人群的房颤患病率为2.1%。在40岁以上人群中,男性患病率为1.2%,女性为0.4%。在65岁以上人群中,男性患病率为3.3%,女性为1.1%。约56.6%接受:2004年10月5日,房颤患者年龄超过65岁。在所有年龄组中,男性AF的患病率均高于女性。此外,AF的患病率在80岁以上的人群中最高。在单因素分析中,男性、老年年龄≥ 65岁、高血压、糖尿病、心电图左心室肥厚、中风和心脏病与房颤风险增加相关。然而,在多变量分析中,房颤的危险因素是男性(比值比,OR 4.1; 95%置信区间[CI]:2.6 - 6.5;,cr-0.000),老年(OR 5.3; 95% CI:3.5至7.9; p = 0.000)和心脏病(OR 19.8; 95% CI:12.3至31.8; p = 0.000)。在这项研究中,房颤最有力的危险因素是心脏病。
Atrial fibrillation (AF) is a common arrhythmia that is a potent independent risk facfor for stroke. The incidence of AF increase with age and most affected people have underlying cardiac disease. This study aimed to describe the prevalence of and risk factors for AF in Korean. In this study, 14,540 adults (male 6,573/female 7,967) >= 40 yr old received screening test for general health between April 2000 and December 2000. Participants answered questionnaires and underwent examinations that included blood pressure, electrocardiogram (ECG), total cholesterol, and fasting glucose. Data analysis was done by SPSS 10.0 for Windows. The prevalence of AF was 0.7% in people older than 40 yr and 2.1% in those older than 65 yr. The prevalence in men was 1.2% and women was 0.4% in people older than 40 yr. The prevalence in menwas 3.3% and women was 1.1% in people older than 65 yr. Approximately 56.6% Accepted: 5 October 2004 of individuals with AF are older than 65 yr. The prevalence of AF was higher at all age group in men than in women. Also, the prevalence of AF was highest in people older than 80 yr. In univariate analysis, male sex, old age (>= 65 yr), hypertension, diabetes mellitus, left ventricular hypertrophy in ECG, stroke, and cardiac disease were associated with an increased risk of AF. In multivariate analysis, however, risk factors of AF were male (odds ratio, OR 4.1; 95% confidence interval [CI] : 2.6 to 6.5;,cr-0.000), old age (OR 5.3; 95% CI:3.5 to 7.9; p = 0.000), and cardiac disease (OR 19.8; 95% Cl: 12.3 to 31.8; p = 0.000). In this study, the most potent risk factors of AF was cardiac disease.