Cytomorphology of primary signet ring‐cell carcinoma of the lung
Cytomorphology of primary signet ring‐cell carcinoma of the lung
复制标题
原发性肺印戒细胞癌的细胞形态学
DOI：
10.1002/dc.20937
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发表时间：
2009
影响因子：
1.3
通讯作者：
D. Wolfson
中科院分区：
文献类型：
--
作者：
N. Jin;C. Nguyen;S. Shuja;R. Makary;D. Wolfson
亲爱的Bedrossian医生：原发性肺印戒细胞癌（SRCC）是一种非常罕见的临床事件，纯粹的SRCC病例很少被报道。SRCC是世界卫生组织分类中公认的肺腺癌的一种变体，并且已知具有独特的临床病理表现。这些肿瘤具有很强的侵袭性，患者的预后通常比其他类型的肺肿瘤更差。我们报告一例罕见的肺印戒细胞癌，在支气管灌洗和刷拭标本以及相应的肺肿瘤支气管活检中研究了印戒细胞的细胞形态学特征。这是第一例来自实际肺原发的SRCC细胞形态学和确证性支气管活检，由于其平淡的细胞学特征和与肺泡巨噬细胞的相似性可能导致错误的细胞学诊断，因此认识到这一点很重要。
Dear Dr. Bedrossian: Primary signet ring-cell carcinoma of the lung (SRCC) is an extraordinary rare clinical event and very few cases of pure SRCC have been described. SRCC is a recognized variant of pulmonary adenocarcinoma in the WHO classification and has been known to have a distinct clinical-pathological presentation. These tumors are known to be highly aggressive and patients typically have a worse prognosis than other lung tumor types. We describe a rare and unusual case of signet ring-cell carcinoma of the lung in which cytomorphological features of signet ring-cells were studied in bronchial lavage and brush specimens as well in corresponding bronchial biopsy from primary lung tumor. This is the first case of cytomorphology of SRCC from the actual lung primary with confirmatory bronchial biopsy, which is important to recognize because of its bland cytologic features and resemblance to alveolar macrophages that may lead to an erroneous cytologic diagnosis.
影响因子：
3.5
作者：
Sakuma, Yuji;Matsukuma, Shoichi;Miyagi, Yohei
通讯作者：
Miyagi, Yohei