SYNTHESIS OF UNSATURATED FATTY ACIDS IN THE SLIME MOLD PHYSARUM POLYCEPHALUM AND THE ZOOFLAGELLATES LEISHMANIA TARENTOLAE, TRYPANOSOMA LEWISI, AND CRITHIDIA SP.: A COMPARATIVE STUDY.
SYNTHESIS OF UNSATURATED FATTY ACIDS IN THE SLIME MOLD PHYSARUM POLYCEPHALUM AND THE ZOOFLAGELLATES LEISHMANIA TARENTOLAE, TRYPANOSOMA LEWISI, AND CRITHIDIA SP.: A COMPARATIVE STUDY.
复制标题
多头粘菌和动鞭毛虫利什曼原虫、路易斯锥虫和 CRITHIDIA SP. 中不饱和脂肪酸的合成：比较研究。
DOI：
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发表时间：
1965
影响因子：
6.5
通讯作者：
A. M. Lees
中科院分区：
文献类型：
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作者：
E. Korn;C. Greenblatt;A. M. Lees
根据它们合成的不饱和脂肪酸，原生生物可以以一种有意义的方式分类。因此，真粘菌的不饱和脂肪酸与土壤阿米巴、棘阿米巴和哈特曼氏菌的不饱和脂肪酸相同，但与细胞粘菌Dictyostelius的不饱和脂肪酸不同。在动物鞭毛虫中，恩里埃蒂利什曼原虫和塔氏利什曼原虫合成的不饱和脂肪酸与植物鞭毛虫Euglena、Ochromonas和Chlamydomonas非常相似，而路易氏锥虫，特别是克里西迪亚纲则有不同的不饱和脂肪酸模式，与纤毛虫的不饱和脂肪酸更相似。多头绒泡菌的不饱和脂肪酸包括油酸、亚油酸、11-二十碳二烯酸酯、11，14-二十碳二烯酸酯、8，11，14-二十碳三烯酸酯和花生四烯酸。狼毒能合成6，9，12-十八碳三烯酸和9，12，15-十八碳三烯酸，以及由这两种18-碳酸衍生的多不饱和20和22-碳脂肪酸。T.路易西合成了6，9，12-十八碳三烯酸酯。甲藻可合成6，9，12十八碳三烯酸酯、8，11，14-二十碳三烯酸酯和4，7，10，13，16二十二碳五烯酸酯，但不合成9，12，15-十八碳三烯酸酯或由此衍生的任何酸。利什曼原虫和锥虫已被证明可以将硬脂酸盐直接转化为油酸盐。
On the basis of the unsaturated fatty acids which they synthesize, protists can be grouped in a meaningful way. Thus, the unsaturated fatty acids of the true slime mold are identical with the unsaturated fatty acids of the soil amoebae Acanthumoeba and Hartmannella but have no resemblance to those of the cellular slime mold Dictyostelium. Among the zooflagellates, Leishmania enriettii and Leishmania tarentolae synthesize unsaturated fatty acids that are very similar to those of the phytoflagellates Euglena, Ochromonas, and Chlamydomonas, while Trypanosoma lewisi and especially Crithidia have a different pattern of unsaturated fatty acids which more closely resembles that of the ciliated protazoa. The unsaturated fatty acids of the true slime mold Physarum polycephulum include oleate, linoleate, 11-eicosenoate, 11,14eicosadienoate, 8,11,14-eicosatrienoate, and arachidonate. L. tarentolae synthesizes 6,9,12-octadecatrienoate and 9,12,15octadecatrienoate as well as polyunsaturated 20and 22-carbon fatty acids derived from both of these 18-carbon acids. T . lewisi synthesizes 6,9,12-octadecatrienoate. Crithidia synthesizes 6,9,12octadecatrienoate, 8,11,14-eicosatrienoate, and 4,7,10,13,16docosapentaenoate but not 9,12,15-octadecatrienoate or any acids derived from it. Leishmania and Trypanosoma have been shown to convert stearate directly to oleate.