Association of Chronic Kidney Disease with Preserved Ejection Fraction Heart Failure Is Independent of Baseline Cardiac Function
Association of Chronic Kidney Disease with Preserved Ejection Fraction Heart Failure Is Independent of Baseline Cardiac Function
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DOI：
10.1159/000502874
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发表时间：
2019-10-01
影响因子：
2.8
通讯作者：
Charytan, David M.
中科院分区：
文献类型：
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作者：
Mavrakanas, Thomas A.;Khattak, Aisha;Charytan, David M.
背景/目的：慢性肾脏病（CKD）在射血分数保留的心力衰竭（HFpEF）患者中很常见，并与较差的临床结局相关。本研究旨在确定CKD与HFpEF的相关性是否独立于基础超声心动图异常。材料：我们进行了一项回顾性队列研究，包括没有心脏衰竭的患者进行超声心动图检查。将连续超声心动图、基线左心室射血分数（LVEF）≥ 50%和估计肾小球滤过率（eGFR）≥ 90 mL/min/1.73 m2的患者与eGFR ≥ 90 mL/min/1.73 m2的患者1：1配对。
Background/Aims: Chronic kidney disease (CKD) is common among patients with heart failure with preserved ejection fraction (HFpEF) and is associated with worse clinical outcomes. This study aims to identify whether the association of CKD with HFpEF is independent of underlying echocardiographic abnormalities. Materials: We conducted a retrospective cohort study including patients without prevalent heart failure referred for echocardiography. Patients with serial echocardiograms, baseline left ventricular ejection fraction (LVEF) >= 50% and estimated glomerular filtration rate (eGFR) >= 90 mL/min/1.73 m(2) were matched 1:1 with patients with eGFR