Spectrin-based skeleton as an actor in cell signaling.
Spectrin-based skeleton as an actor in cell signaling.
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DOI:
10.1007/s00018-011-0804-5
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发表时间:
2012-01
影响因子:
8
通讯作者:
Lecomte, M. C.
中科院分区:
文献类型:
--
作者:
Machnicka, B.;Grochowalska, R.;Boguslawska, D. M.;Sikorski, A. F.;Lecomte, M. C.
This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the commonly known role of the spectrin-based skeleton in control of membrane organization, stability and shape, and tethering protein mosaics to the cellular motors and to all major filament systems. Particular effort has been undertaken to highlight recent advances linking spectrin to cell signaling phenomena and its participation in signal transduction pathways in many cell types.
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