AN INVESTIGATION INTO THE INCIDENCE OF AUTOIMMUNE DISORDERS IN PATIENTS WITH LICHEN SCLEROSUS AND ATROPHICUS
AN INVESTIGATION INTO THE INCIDENCE OF AUTOIMMUNE DISORDERS IN PATIENTS WITH LICHEN SCLEROSUS AND ATROPHICUS
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DOI：
10.1111/j.1365-2133.1981.tb08172.x
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发表时间：
1981-01-01
影响因子：
10.3
通讯作者：
DUNSMORE, IR
中科院分区：
文献类型：
--
作者：
HARRINGTON, CI;DUNSMORE, IR
硬化性苔藓和萎缩性苔藓患者器官特异性抗体的发生率增加。这些患者及其亲属的相关自身免疫性疾病的发病率明显高于对照人群。硬化性苔藓患者中其他自身免疫性疾病的发病率在41 ~ 60岁之间发病时最高，但与病变的持续时间或部位无关。提出了本病的免疫学基础。应对患者进行调查和随访，以检测是否存在其他自身免疫性疾病。
Patients with lichen sclerosus and atrophicus have an increased incidence of organ specific antibodies. These patients and their relatives have a significantly higher incidence of associated autoimmune diseases than a control population. The incidence of other autoimmune diseases in patients with lichen sclerosus is highest when the onset is between the ages of 41 and 60 yr, but is not related to the duration or site of the lesions. An immunological basis for the disease is suggested. Patients should be investigated and followed up to detect the existence of other autoimmune disorders.