The roots of empathy: Through the lens of rodent models.
The roots of empathy: Through the lens of rodent models.
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DOI：
10.1016/j.neubiorev.2016.10.028
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发表时间：
2017-05
影响因子：
8.2
通讯作者：
Knapska E
中科院分区：
文献类型：
--
作者：
Meyza KZ;Bartal IB;Monfils MH;Panksepp JB;Knapska E
同理心是一种通常被认为依赖于高阶情绪控制和理解他人情绪状态的能力的现象。许多人认为，这只是因为物种拥有发达的皮质回路，能够执行如此复杂的任务。然而，多年来积累的大量数据表明，啮齿类动物不仅能够分享同类的情绪状态，而且还能够在这种共同经历的推动下做出亲社会行为。啮齿动物共情行为的研究现在才成为一个独立的研究领域。相关动物模型可以精确操纵神经网络，从而深入了解哺乳动物大脑中同理心的基础。在这里，我们回顾了大鼠和小鼠模型中共情行为的数据、它们的神经生物学和神经生理学相关性以及影响这些行为的因素。我们讨论简单的啮齿动物共情模型如何增强我们对大脑如何控制共情行为的理解。
Empathy is a phenomenon often considered dependent on higher-order emotional control and an ability to relate to the emotional state of others. It is, by many, attributed only to species having well-developed cortical circuits capable of performing such complex tasks. However, over the years, a wealth of data has been accumulated showing that rodents are capable not only of sharing emotional states of their conspecifics, but also of prosocial behavior driven by such shared experiences. The study of rodent empathic behaviors is only now becoming an independent research field. Relevant animal models allow precise manipulation of neural networks, thereby offering insight into the foundations of empathy in the mammalian brains. Here we review the data on empathic behaviors in rat and mouse models, their neurobiological and neurophysiological correlates, and the factors influencing these behaviors. We discuss how simple rodent models of empathy enhance our understanding of how brain controls empathic behaviors.