ULTRASTRUCTURE OF RETINAL PIGMENT EPITHELIUM OF HUMAN FETUS
ULTRASTRUCTURE OF RETINAL PIGMENT EPITHELIUM OF HUMAN FETUS
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DOI：
10.1016/s0022-5320(66)80008-4
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发表时间：
1966-01-01
期刊：
影响因子：
--
通讯作者：
WYLLIE, LMA
中科院分区：
文献类型：
--
作者：
BREATHNA.AS;WYLLIE, LMA
研究人员对 6 个 8 至 14 周的人类胎儿的眼睛视网膜色素上皮的超微结构进行了研究。与完全发育状态相比，描述了不同阶段细胞的细胞质和质膜的一般特征。视网膜细胞色素颗粒的发育模式与表皮黑素细胞内发生的模式基本相似。可能源自高尔基体的小型膜限制性囊泡变得更大且呈卵圆形，并获得同心或折叠内膜系统，黑色素沉积在其上。颗粒内膜的精细结构以及它们黑化的方式同样相似。
The ultrastructure of retinal pigment epithelium was studied in eyes of six human fetuses ranging in age from 8 to 14 weeks. General features of the cytoplasm and plasma membranes of cells at different stages are described, in comparison with the fully developed condition. The mode of development of the pigment granules of retinal cells is essentially similar to that occurring within the epidermal melanocytes. Small, membrane-limited vesicles, probably of Golgi origin, become larger and ovoid in shape, and acquire a system of concentric or folded inner membranes upon which melanin is deposited. The fine structure of the inner membranes of the granules and the manner in which they become melanized is likewise similar.