Determinants in Adolescence of Stroke-Related Hospital Stay Duration in Men: A National Cohort Study.
Determinants in Adolescence of Stroke-Related Hospital Stay Duration in Men: A National Cohort Study.
复制标题
男性中风相关住院时间青春期的决定因素：一项全国队列研究。
DOI：
10.1161/strokeaha.116.014265
复制
发表时间：
2016
期刊：
影响因子：
8.3
通讯作者：
Bergh C
中科院分区：
文献类型：
--
作者：
Bergh C
背景和目的青少年的生理和心理特征与随后的卒中风险相关。我们的目的是调查其相关性的住院时间和风险的第二stroke.MethodsSwedish男性出生于1952年和1956年之间（n=237 879），从1987年至2010年使用的信息，以人口为基础的国家登记。压力恢复力，身体质量指数，认知功能，体能和血压在青春期后期的强制征兵考试。联合考克斯比例风险模型估计这些特征的协会与长期相比，中风相关的住院时间短，与第二次中风相比，first.Results3000名男子被诊断为非致命性中风之间的年龄31和58岁。压力恢复能力低，体重不足，收缩压较高（每增加1毫米汞柱）与住院时间延长有关（与较短时间相比）在缺血性卒中中的作用，校正相对风险比（和95%置信区间）分别为1.46（1.08-1.89）、1.41（1.04-1.91）和1.01（1.00-1.02）。青春期收缩压和舒张压升高与脑出血患者住院时间延长相关：分别为1.01（1.00-1.03）和1.02（1.00-1.04）。在这两种类型的中风，肥胖在青春期赋予了增加的风险，第二次中风：2.06（1.21-3.45）。ConclusionsSome特性相关的中风相关的住院时间和风险的第二次中风的长度已经存在于青春期。早期生活方式的影响不仅对中年中风风险很重要，而且对中风幸存者的复发和医疗资源的使用也很重要。
Background and PurposePhysical and psychological characteristics in adolescence are associated with subsequent stroke risk. Our aim is to investigate their relevance to length of hospital stay and risk of second stroke.MethodsSwedish men born between 1952 and 1956 (n=237 879) were followed from 1987 to 2010 using information from population-based national registers. Stress resilience, body mass index, cognitive function, physical fitness, and blood pressure were measured at compulsory military conscription examinations in late adolescence. Joint Cox proportional hazards models estimated the associations of these characteristics with long compared with short duration of stroke-related hospital stay and with second stroke compared with first.ResultsSome 3000 men were diagnosed with nonfatal stroke between ages 31 and 58 years. Low stress resilience, underweight, and higher systolic blood pressure (per 1-mm Hg increase) during adolescence were associated with longer hospital stay (compared with shorter) in ischemic stroke, with adjusted relative hazard ratios (and 95% confidence intervals) of 1.46 (1.08–1.89), 1.41 (1.04–1.91), and 1.01 (1.00–1.02), respectively. Elevated systolic and diastolic blood pressures during adolescence were associated with longer hospital stay in men with intracerebral hemorrhage: 1.01 (1.00–1.03) and 1.02 (1.00–1.04), respectively. Among both stroke types, obesity in adolescence conferred an increased risk of second stroke: 2.06 (1.21–3.45).ConclusionsSome characteristics relevant to length of stroke-related hospital stay and risk of second stroke are already present in adolescence. Early lifestyle influences are of importance not only to stroke risk by middle age but also to recurrence and use of healthcare resources among stroke survivors.