Comparison of the efficacy of diclofenac, acupuncture, and acetaminophen in the treatment of renal colic
Comparison of the efficacy of diclofenac, acupuncture, and acetaminophen in the treatment of renal colic
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DOI：
10.1016/j.ajem.2015.02.033
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发表时间：
2015-06-01
影响因子：
3.6
通讯作者：
Ceylan, Kadir
中科院分区：
文献类型：
--
作者：
Kaynar, Mehmet;Koyuncu, Ferudun;Ceylan, Kadir
目的：目的：比较双氯芬酸、对乙酰氨基酚和针刺对尿石症肾绞痛的镇痛效果。治疗组40例采用对乙酰氨基酚静脉滴注，对照组41例采用针刺，对照组40例采用双氯芬酸钠75 mg肌肉注射。10、30、60和120分钟后，使用视觉模拟量表（VAS）和言语评定量表（VRS）评估疼痛强度。结果：基线VAS或VRS在年龄或性别方面无显着差异。10分钟后，所有3组的VAS和VRS评分均显著降低，其中组II的降低幅度最大。30分钟后，III组的下降幅度明显高于I组（P= 0.001）。60分钟后，组I和组III的平均VAS评分相似（P= 0.753）。III组的平均VAS评分低于II组（P= 0.013）。120分钟后，I组和II组之间以及II组和III组之间的VAS评分差异为（P= 0.000）。然而，120分钟后进行的VAS评价显示，第I组和第III组的结局在统计学上相似（P=.488）。VRS评估后10，30，60，和120的统计结果是相似的VAS.Conclusions：在肾绞痛患者与可能的非甾体抗炎药和对乙酰氨基酚副作用的风险，针灸出现作为一种替代治疗方式。(C)2015 Elsevier Inc. All rights reserved.
Objective: The objective is to compare the analgesic effects of diclofenac, acetaminophen, and acupuncture in urolithiasis-driven renal colic pain relief.Methods: Renal colic patients were divided randomly into 3 groups. Patients in group I (n = 40) were treated with intravenous acetaminophen, those in group II (n = 41) with acupuncture, and those in group III (n = 40) with a 75-mg intramuscular injection diclofenac sodium. Visual analogue scale (VAS) and verbal rating scale (VRS) were used to assess pain intensity after 10, 30, 60, and 120 minutes.Results: No significant differences in baseline VAS or VRS were found with regard to age or sex. After 10 minutes, all 3 groups experienced a significant decrease in VAS and VRS scores, with the most drastic decrease occurring in group II. After 30 minutes, there was a significantly higher decrease in group III than in group I (P=.001). After 60 minutes, mean VAS scores of groups I and III (P=.753) were similar. The mean VAS score of group III was lower than that of group II (P=.013). After 120 minutes, the difference in the VAS scores was (P=.000) between groups I and II and between groups II and III. Yet, the VAS evaluation made after 120 minutes revealed statistically similar outcomes for groups I and III (P=.488). The statistical findings for VRS evaluations made after 10, 30, 60, and 120 were similar to those for VAS.Conclusions: In renal colic patients with a possible nonsteroidal anti-inflammatory drug and acetaminophen side effect risk, acupuncture emerges as an alternative treatment modality. (C) 2015 Elsevier Inc. All rights reserved.