Wolbachia and Virus Protection in Insects
Wolbachia and Virus Protection in Insects
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DOI：
10.1126/science.1162418
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发表时间：
2008-10-31
期刊：
影响因子：
56.9
通讯作者：
Johnson, Karyn N.
中科院分区：
文献类型：
--
作者：
Hedges, Lauren M.;Brownlie, Jeremy C.;Johnson, Karyn N.
Wolbachia pipientis 细菌是昆虫常见的内共生体，其最著名的是它们能够通过操纵宿主生殖系统来增加其在种群中的流行率。然而，自然界中存在一些沃尔巴克氏体，它们似乎不具有生殖寄生性状，但却能够侵入种群。我们证明了感染沃尔巴克氏体的昆虫的健康益处，这可以解释这一悖论。感染沃尔巴克氏体的果蝇不太容易受到一系列 RNA 病毒引起的死亡的影响。与沃尔巴克氏体感染相关的抗病毒保护可能会在未来减少昆虫病原体传播的策略中得到利用。
Wolbachia pipientis bacteria are common endosymbionts of insects that are best known for their ability to increase their prevalence in populations by manipulating host reproductive systems. However, there are examples of Wolbachia that exist in nature that seem to induce no reproductive parasitism trait and yet are able to invade populations. We demonstrate a fitness benefit for Wolbachia-infected insects that may explain this paradox. Drosophila melanogaster flies infected with Wolbachia are less susceptible to mortality induced by a range of RNA viruses. The antiviral protection associated with Wolbachia infection might be exploited in future strategies to reduce transmission of pathogens by insects.