Adaptive Statistical Iterative Reconstruction Technique for Radiation Dose Reduction in Chest CT: A Pilot Study
Adaptive Statistical Iterative Reconstruction Technique for Radiation Dose Reduction in Chest CT: A Pilot Study
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DOI：
10.1148/radiol.11101450
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发表时间：
2011-05-01
期刊：
影响因子：
19.7
通讯作者：
Shepard, Jo-Anne O.
中科院分区：
文献类型：
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作者：
Singh, Sarabjeet;Kalra, Mannudeep K.;Shepard, Jo-Anne O.
目的：比较不同管电流时间积（40-150 mAs）下胸部CT图像的病变检测和图像质量，并采用自适应统计迭代重建（ASIR）和滤波反投影（FBP）重建。材料和方法：在这项机构审查委员会批准的符合hipaa的研究中，来自23名患者（平均年龄63岁+/- 7.3[标准差]；10名男性，13名女性）的CT数据在64排10cm扫描长度的多检测器CT扫描仪上获得不同管电流时间产品（40、75、110和150 mAs）的CT数据。所有患者均给予知情同意。在30%、50%和70%的ASIR-FBP混合下重建数据集。两名胸部放射科医生评估了图像噪声、小结构的可见性、病变的显著性和诊断的可信度。测量胸主动脉的客观噪声和CT数。记录CT剂量指数、体积、剂量长积、体重、横径。数据分析采用方差分析和Wilcoxon符号秩检验。结果：FBP在40和75 ma时分别有17例和5例患者具有不可接受的噪声，而ASIR在40-150 ma时具有可接受的噪声。30%， 50%和70% ASIR混合（分别为11.8 +/- 3.8,9.6 +/- 3.1和7.5 +/- 2.6）的客观噪声低于FBP (15.8 +/- 4.8) （P < 0.0001）。FBP和ASIR图像均未遗漏病灶。在FBP和ASIR图像上均可见病变明显程度分级（P < 0.05）。70%的混合ASIR图像显示轻微的像素化斑点纹理。结论：应用ASIR在40mas下获得的胸部CT图像质量可以接受，没有明显的伪影影响诊断的可信度。(C) RSNA, 2011年
Purpose: To compare lesion detection and image quality of chest computed tomographic (CT) images acquired at various tube current-time products (40-150 mAs) and reconstructed with adaptive statistical iterative reconstruction (ASIR) or filtered back projection (FBP).Materials and Methods: In this Institutional Review Board-approved HIPAA-compliant study, CT data from 23 patients (mean age, 63 years +/- 7.3 [standard deviation]; 10 men, 13 women) were acquired at varying tube current-time products (40, 75, 110, and 150 mAs) on a 64-row multidetector CT scanner with 10-cm scan length. All patients gave informed consent. Data sets were reconstructed at 30%, 50%, and 70% ASIR-FBP blending. Two thoracic radiologists assessed image noise, visibility of small structures, lesion conspicuity, and diagnostic confidence. Objective noise and CT number were measured in the thoracic aorta. CT dose index volume, dose-length product, weight, and transverse diameter were recorded. Data were analyzed by using analysis of variance and the Wilcoxon signed rank test.Results: FBP had unacceptable noise at 40 and 75 mAs in 17 and five patients, respectively, whereas ASIR had acceptable noise at 40-150 mAs. Objective noise with 30%, 50%, and 70% ASIR blending (11.8 +/- 3.8, 9.6 +/- 3.1, and 7.5 +/- 2.6, respectively) was lower than that with FBP (15.8 +/- 4.8) (P < .0001). No lesions were missed on FBP or ASIR images. Lesion conspicuity was graded as well seen on both FBP and ASIR images (P < .05). Mild pixilated blotchy texture was noticed with 70% blended ASIR images.Conclusion: Acceptable image quality can be obtained for chest CT images acquired at 40 mAs by using ASIR without any substantial artifacts affecting diagnostic confidence. (C)RSNA, 2011