The representation of occluded image regions in area V1 of monkeys and humans.
The representation of occluded image regions in area V1 of monkeys and humans.
复制标题
猴子和人类 V1 区域中被遮挡图像区域的表示。
DOI：
10.1016/j.cub.2023.08.010
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Papale P
中科院分区：
文献类型：
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作者：
Papale P
初级视觉皮层（V1）的神经元活动由神经元接受野（RF）内的前馈输入驱动，并由RF周围区域的环境信息调节。上下文信息对尖峰活动的影响发生得很快，因此很难与前馈输入分离。为了解决这一挑战，我们记录了猴子在观看自然场景或RF信息被遮挡的场景时V1神经元的尖峰活动，有效地消除了前馈输入。我们发现V1神经元对被遮挡的场景有快速和选择性的反应。被遮挡的刺激引发的V1反应可以用来解码单个场景，并且可以从未被遮挡的图像引发的V1反应中进行预测，这表明视觉驱动和上下文反应之间存在重叠。我们使用表征相似性分析表明，用电生理学测量的猴子被遮挡场景的V1表征结构与用功能磁共振成像（fMRI）测量的人类相同场景的表征具有很强的相关性。我们的研究结果表明，环境影响会迅速改变猴子在视野范围内几度距离上的V1尖峰活动，携带有关单个场景的信息，与人类V1类似。视频摘要
Neuronal activity in the primary visual cortex (V1) is driven by feedforward input from within the neurons' receptive fields (RFs) and modulated by contextual information in regions surrounding the RF. The effect of contextual information on spiking activity occurs rapidly and is therefore challenging to dissociate from feedforward input. To address this challenge, we recorded the spiking activity of V1 neurons in monkeys viewing either natural scenes or scenes where the information in the RF was occluded, effectively removing the feedforward input. We found that V1 neurons responded rapidly and selectively to occluded scenes. V1 responses elicited by occluded stimuli could be used to decode individual scenes and could be predicted from those elicited by non-occluded images, indicating that there is an overlap between visually driven and contextual responses. We used representational similarity analysis to show that the structure of V1 representations of occluded scenes measured with electrophysiology in monkeys correlates strongly with the representations of the same scenes in humans measured with functional magnetic resonance imaging (fMRI). Our results reveal that contextual influences rapidly alter V1 spiking activity in monkeys over distances of several degrees in the visual field, carry information about individual scenes, and resemble those in human V1.Video abstract