Silver ion release from antimicrobial polyamide/silver composites
Silver ion release from antimicrobial polyamide/silver composites
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DOI：
10.1016/j.biomaterials.2004.05.030
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发表时间：
2005-05-01
期刊：
影响因子：
14
通讯作者：
Münstedt, H
中科院分区：
文献类型：
--
作者：
Kumar, R;Münstedt, H
银离子 (Ag+) 这种多功能抗菌物质在银填充聚酰胺复合材料系统中以稳定且持久的方式释放。具有不同比表面积（SSA）的金属银粉末已被用作聚酰胺中的杀菌剂来源。强有力的证据表明，由于扩散的水分子与基质内分散的银粉的相互作用，将所得复合材料浸泡在水中后，抗菌物质从所得复合材料中释放出来。观察到Ag+释放随着时间和银粉浓度的增加而增加，并且发现Ag+释放受到银粉SSA的影响，由于水扩散和复合形态而导致复合样本的物理状态变化。据观察，Ag+ 释放量最初增加，随后在第 4 天和第 6 天之间哺乳动物增加。含有较高量银（4 和 8wt%）的复合材料从在水中储存第六天开始，Ag+ 释放量进一步增加。含有最低比表面积 (0.78 m(2)/g) 银颗粒的复合材料显示出最高的 Ag+ 释放量。 SEM 显示具有最低 SSA 的银粉（4 wt%）的更精细分散。然而，SSA 较高（1.16 和 2.5m(2)/g）的颗粒具有团聚形态，导致 Ag+ 释放量较低。研究发现该复合材料能够以能够提供抗菌功效的浓度水平释放Ag+。 (C) 2004 爱思唯尔有限公司。版权所有。
Silver ion (Ag+) the versatile antimicrobial species was released in a steady and prolonged manner front a silver-filled polyamide composite system. Metallic silver powder having varying specific surface area (SSA) has been used as a resource of biocide in polyamide. Strong evidences are found showing the release of the antimicrobial species from the resulting composite upon Soaking it in water due to the interaction of the diffused water molecules with the dispersed silver powder within the matrix. The Ag+ release was observed as increasing with time and concentration of the silver powder and is found to he influenced by the SSA of the silver powder changes in the physical state of the composite specimen as a result of the water diffusion and the composite morphology. It is observed that the Ag+ release increases initially which is followed by a mammal increase between day 4 and 6. Composites containing higher amounts of silver (4 and 8wt%) exhibit a further rise in Ag+ release from the sixth day of storage in water. Composite containing silver particles with the lowest specific surface area (0.78 m(2)/g) showed highest Ag+ release. SEM shows a finer dispersion of the silver powder (4 wt%) having lowest SSA. However particles with higher (1.16 and 2.5m(2)/g) SSA Possess an agglomerated morphology leading to lower Ag+ release. The composites are found to release Ag+ at a concentration level capable of rendering an antimicrobial efficacy. (C) 2004 ElsevierLtd. All rights reserved.