Real-Time Measurements of Botanical Disinfectant Emissions, Transformations, and Multiphase Inhalation Exposures in Buildings
Real-Time Measurements of Botanical Disinfectant Emissions, Transformations, and Multiphase Inhalation Exposures in Buildings
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DOI：
10.1021/acs.estlett.1c00390
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发表时间：
2021-06-09
影响因子：
10.9
通讯作者：
Boor, Brandon E.
中科院分区：
文献类型：
--
作者：
Jiang, Jinglin;Ding, Xiaosu;Boor, Brandon E.
基于百里香的植物消毒剂已成为传统化学消毒剂的天然替代品，因为它们具有抗菌农药的有效性和灭活SARS-CoV-2的能力。本研究探讨植物消毒剂对室内空气化学及人体暴露的影响。控制表面消毒实验在机械通风的零能耗微型房屋实验室进行。利用质子转移反应飞行时间质谱仪和高分辨率低压电冲击器实时（1hz）测量挥发性有机化合物（VOCs）和气溶胶大小分布。植物消毒剂喷雾和擦拭产品使室内空气的化学成分发生了突然的变化。单萜类化合物（C10H16）和单萜类化合物（C10H14O、C10H16O、C10H18O和C10H20O）的混合比在消毒过程中突然增加（10（-1）至10(2)ppb），并表现出挥发性相关的时间排放曲线。挥发性有机化合物的排放系数在100到10(4)μ g（-1）之间，百里香酚的摄入分数在6到7 × 10(3) ppm之间。单萜烯和单萜类化合物由于臭氧分解而快速形成新颗粒，使100 nm以下的颗粒数量浓度增加10(4)至10(5)cm（-3）。植物性消毒喷雾引发了挥发性有机化合物、二次有机气溶胶和低于10 μ m液滴的多相吸入暴露，后两者在每个呼吸道区域的沉积剂量都很大。
Thymol-based botanical disinfectants have emerged as natural alternatives to traditional chemical disinfectants given their effectiveness as antimicrobial pesticides and ability to inactivate SARS-CoV-2. This study investigates the impact of botanical disinfectants on indoor air chemistry and human exposure. Controlled surface disinfection experiments were conducted in a mechanically ventilated zero-energy tiny house laboratory. Volatile organic compounds (VOCs) and aerosol size distributions were measured in real-time (1 Hz) with a proton transfer reaction time-of-flight mass spectrometer and a high-resolution electrical low-pressure impactor, respectively. Botanical disinfectant spray and wipe products drove sudden changes in the chemical composition of indoor air. Mixing ratios of monoterpenes (C10H16) and monoterpenoids (C10H14O, C10H16O, C10H18O, and C10H20O) increased suddenly during the disinfection events (10(-1) to 10(2) ppb) and exhibited volatility-dependent temporal emission profiles. VOC emission factors ranged from 100 to 10(4) mu g g(-1), and thymol intake fractions ranged from 6 to 7 x 10(3) ppm. Rapid new particle formation events were observed due to ozonolysis of monoterpenes and monoterpenoids, increasing sub-100 nm particle number concentrations by 10(4) to 10(5) cm(-3). Botanical disinfectant sprays initiated multiphase inhalation exposure to VOCs, secondary organic aerosol, and sub-10 mu m droplets, with large deposited doses in each respiratory tract region associated with the latter two.