PSYCHIATRIC COMORBIDITY IN TREATMENT-SEEKING ANOREXICS AND BULIMICS

PSYCHIATRIC COMORBIDITY IN TREATMENT-SEEKING ANOREXICS AND BULIMICS
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DOI:
10.1097/00004583-199209000-00006
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发表时间:
1992-09-01
影响因子:
13.3
通讯作者:
LAVORI, PW
LAVORI, PW
中科院分区:
医学1区
文献类型:
--
作者:
HERZOG, DB;KELLER, MB;LAVORI, PW

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对229例寻求治疗的女性神经性厌食症(N=41)、神经性贪食症(N=98)和混合性神经性厌食症和神经性贪食症(N=90)的现症和终生精神病诊断进行了比较。所有受试者都接受了情感障碍和精神分裂症-终生版的访谈,其中修改包括关于DSM-III-R饮食障碍的部分,纵向间隔随访评估,以及DSM-III人格障碍的结构化访谈。73%的神经性厌食症受试者、60%的神经性贪食症受试者以及82%的混合性神经性厌食症和神经性贪食症受试者目前诊断为轴心I。重度抑郁症是最常见的被诊断为共病的疾病。酒精和药物滥用障碍的发生率很低,样本中的一小部分出现了人格障碍。混合性精神障碍患者的盗窃症终生患病率高于厌食症患者或暴食症患者。在进食障碍样本中注意到高水平的共病。混合性精神障碍患者的精神病理表现最多,尤其值得进一步研究。
Current and lifetime psychiatric diagnoses were compared in 229 female patients seeking treatment for current episodes of anorexia nervosa (N = 41), bulimia nervosa (N = 98) and mixed anorexia nervosa and bulimia nervosa (N = 90). All subjects were interviewed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version, which was modified to include a section for DSM-III-R eating disorders, the Longitudinal Interval Follow-up Evaluation, and the Structured Interview for DSM-III Personality Disorders. Seventy-three percent of the anorexia nervosa subjects, 60% of the bulimia nervosa subjects, and 82% of the mixed anorexia nervosa and bulimia nervosa subjects had a current comorbid Axis I diagnosis. Major depression was the most commonly diagnosed comorbid disorder. Low rates of alcohol and substances abuse disorder were diagnosed, and personality disorder occurred in a minority of the sample. The subjects with mixed disorder manifested a higher lifetime prevalence of kleptomania than either the anorexics or the bulimics. High levels of comorbidity were noted across the eating disorder samples. Mixed disorder subjects manifested die most comorbid psychopathology and especially warrant further study.