Left frontal eye field encodes sound locations during passive listening
Left frontal eye field encodes sound locations during passive listening
复制标题
左额眼场在被动聆听期间对声音位置进行编码
DOI：
10.1093/cercor/bhac261
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发表时间：
2022
期刊：
影响因子：
3.7
通讯作者：
Juan Zhang
中科院分区：
文献类型：
--
作者：
Liwei Sun;Chunlin Li;Songjian Wang;Qian Si;Meng Lin;Ningyu Wang;Jun Sun;Hongjun Li;Ying Liang;Jing Wei;Xu Zhang;Juan Zhang
Previous studies reported that auditory cortices (AC) were mostly activated by sounds coming from the contralateral hemifield. As a result, sound locations could be encoded by integrating opposite activations from both sides of AC (“opponent hemifield coding”). However, human auditory “where” pathway also includes a series of parietal and prefrontal regions. It was unknown how sound locations were represented in those high-level regions during passive listening. Here, we investigated the neural representation of sound locations in high-level regions by voxel-level tuning analysis, regions-of-interest-level (ROI-level) laterality analysis, and ROI-level multivariate pattern analysis. Functional magnetic resonance imaging data were collected while participants listened passively to sounds from various horizontal locations. We found that opponent hemifield coding of sound locations not only existed in AC, but also spanned over intraparietal sulcus, superior parietal lobule, and frontal eye field (FEF). Furthermore, multivariate pattern representation of sound locations in both hemifields could be observed in left AC, right AC, and left FEF. Overall, our results demonstrate that left FEF, a high-level region along the auditory “where” pathway, encodes sound locations during passive listening in two ways: a univariate opponent hemifield activation representation and a multivariate full-field activation pattern representation.
