Experimental developments in movement disorders: update on proposed free radical mechanisms.
Experimental developments in movement disorders: update on proposed free radical mechanisms.
复制标题
运动障碍的实验进展：提议的自由基机制的更新。
DOI：
10.1097/00019052-199808000-00009
复制
发表时间：
1998
影响因子：
4.8
通讯作者：
Jackson-Lewis,V
中科院分区：
文献类型：
--
作者：
Przedborski,S;Jackson-Lewis,V
Free radicals have been implicated in the pathogenesis of movement disorders such as Parkinson’s disease and Huntington’s disease. Some basic aspects about free radicals as they relate to oxidative stress in neurodegeneration are summarized. Old and new experimental findings pertinent to oxidative damage in movement disorders are reviewed. Finally, the degree to which toxin‐induced and genetically engineered experimental models have been useful in delineating parts of the mechanisms involved in the cascade of events that lead to neuronal death is emphasized. Curr Opin Neurol 11: 335–339.© 1998 Lippincott–Raven Publishers
